33228-44-3

Basic information

• Product Name: 4-PENTYLANILINE
• Synonyms: 4-pentyl-benzenamin;Benzenamine, 4-pentyl-;p-n-Amylaniline;p-n-Pentylaniline;4-N-AMYLANILINE;4-N-PENTYLANILINE;4-PENTYLANILINE;P-PENTYLANILINE
• CAS NO: 33228-44-3
• Molecular Formula: C₁₁H₁₇N
• Molecular Weight: 163.26
• EINECS: 251-409-8
• Product Categories: Alkyl;Alkylanilines;Anilines (Building Blocks for Liquid Crystals);Building Blocks for Liquid Crystals;Functional Materials;Amines;C11 to C38;Nitrogen Compounds
• Mol File: 33228-44-3.mol
• Article Data: 10

Chemical Properties

• Melting Point: 46.25°C (estimate)
• Boiling Point: 130 °C
• Flash Point: >230 °F
• Appearance: /
• Density: 0.919 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.00862mmHg at 25°C
• Refractive Index: n20/D 1.53(lit.)
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 5.10±0.10(Predicted)
• Water Solubility: Sparingly soluble in water.
• CAS DataBase Reference: 4-PENTYLANILINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-PENTYLANILINE(33228-44-3)
• EPA Substance Registry System: 4-PENTYLANILINE(33228-44-3)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• TSCA: Yes
• Hazardous Substances Data: 33228-44-3(Hazardous Substances Data)

Usage

Description

4-Pentyl aniline, also known as N-(pentyl)aniline, is an organic compound with the chemical formula C11H17N. It is a derivative of aniline, where a pentyl group is attached to the nitrogen atom. 4-PENTYLANILINE is characterized by its amine and aromatic ring structures, which contribute to its chemical properties and potential applications.

Uses

Used in Chemical Synthesis:
4-Pentyl aniline is used as a chemical intermediate in the synthesis of various organic compounds. Its amine and aromatic ring structures make it a versatile building block for the production of dyes, pigments, and other specialty chemicals.
Used in the Synthesis of 4-[(4′-pentyl)azo]phenol (5Az-OH):
4-Pentyl aniline is specifically used in the synthesis of 4-[(4′-pentyl)azo]phenol (5Az-OH) through a diazo-coupling reaction with phenol. This reaction involves the formation of a diazonium compound from 4-pentyl aniline, which then reacts with phenol to form the azo compound 5Az-OH. 4-PENTYLANILINE may have potential applications in various fields, such as dyes, pigments, or other specialty chemicals, depending on its properties and performance.

InChI:InChI=1/C11H17N/c1-2-3-4-5-10-6-8-11(12)9-7-10/h6-9H,2-5,12H2,1H3

Upstream product

• 2655-27-8 N-pentylaniline 
• 71-41-0 pentan-1-ol 
• 62-53-3 aniline 
• 142-04-1 aniline hydrochloride 
• 95857-32-2 1-(4-nitrophenyl)pentane 
• 693-03-8 n-butyl magnesium bromide 
• 129075-89-4 4-[(benzotriazol-1-yl)methyl]phenylamine 
• 538-68-1 pentylbenzene 
• 110-53-2 1-Bromopentane 
• 1009-14-9 phenyl butyl ketone 
• 638-29-9 n-valeryl chloride 
• 71-43-2 benzene 
• 4737-50-2 n-pentylboronic acid 
• 17763-80-3 para-nitrophenyl triflate 

Downstream Products

• 102556-64-9 N-(4-butyl-phenyl)-N'-(4-pentyl-phenyl)-thiourea 
• 20330-52-3 N-(4-pentylphenyl)acetamide 
• 2046-10-8 toluene-4-sulfonic acid-(4-pentyl-anilide) 
• 42243-38-9 5-Ethoxy-2-{[(E)-4-pentyl-phenylimino]-methyl}-phenol 
• 142581-09-7 2-(4-Pentyl-phenylamino)-1,9-dihydro-purin-6-one 
• 99338-03-1 C₂₀H₂₇N₃O₃S 
• 37592-87-3 4,4′-dipentylazoxybenzene 
• 73150-52-4 p-Chlorbenzyliden-p-n-pentylanilin 
• 39777-06-5 N-(p-n-pentyloxy benzylidene)-p-n-pentyl aniline 
• 35047-04-2 N-(p-propoxybenzylidene)-p-pentylaniline 
• 39777-05-4 N-(p-butoxybenzylidene)-p-pentylaniline 
• 79098-12-7 Malonsaeurebis(4-pentylanilid) 
• 85017-60-3 4-iodine-pentyl benzene 
• 191719-16-1 6-pentyl-benzothiazol-2-ylamine 

Relevant articles and documents

Pathways in the Degradation of Geminal Diazides

The degradation of geminal diazides is described. We show that diazido acetates are converted into tetrazoles through the treatment with bases. The reaction of dichloro ketones with azide anions provides acyl azides, through in situ formation of diazido ketones. We present experimental and theoretical evidence that both fragmentations may involve the generation of acyl cyanide intermediates. The controlled degradation of terminal alkynes into amides (by loss of one carbon) or ureas (by loss of two carbons) is also shown.

Design and synthesis of boronic acid inhibitors of endothelial lipase

Endothelial lipase (EL) and lipoprotein lipase (LPL) are homologous lipases that act on plasma lipoproteins. EL is predominantly a phospholipase and appears to be a key regulator of plasma HDL-C. LPL is mainly a triglyceride lipase regulating (V)LDL levels. The existing biological data indicate that inhibitors selective for EL over LPL should have anti-atherogenic activity, mainly through increasing plasma HDL-C levels. We report here the synthesis of alkyl, aryl, or acyl-substituted phenylboronic acids that inhibit EL. Many of the inhibitors evaluated proved to be nearly equally potent against both EL and LPL, but several exhibited moderate to good selectivity for EL.

Novel routes to 4-substituted N,N-dialkylanilines, N-alkylanilines and anilines

4-(Benzotriazol-1-ylmethyl)-N,N-dialkylanilines, -N-alkylanilines, -anilines and some substituted analogs obtained via lithiation are converted by lithium aluminum hydride or Grignard reagents into 4-substituted N,N-dialkylanilines, N-alkylanilines and anilines, respectively, in good yields.