332345-27-4 Usage
General Description
5-Morpholinothiophene-2-carboxylic acid is a chemical compound with the molecular formula C9H11NO3S. It is a thienylcarboxylic acid derivative with a morpholine group. 5-Morpholinothiophene-2-carboxylic acid is a potential building block for the synthesis of various pharmaceuticals and agrochemicals. It acts as a molecular scaffold for the design of new drugs and has shown promising biological activities in preliminary studies. The morpholine moiety in its structure contributes to its potential use in medicinal chemistry, as morpholine-containing compounds are known for their diverse pharmacological activities. Overall, 5-Morpholinothiophene-2-carboxylic acid is a versatile chemical that holds potential for various applications in drug discovery and development.
Check Digit Verification of cas no
The CAS Registry Mumber 332345-27-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,3,2,3,4 and 5 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 332345-27:
(8*3)+(7*3)+(6*2)+(5*3)+(4*4)+(3*5)+(2*2)+(1*7)=114
114 % 10 = 4
So 332345-27-4 is a valid CAS Registry Number.
InChI:InChI=1/C9H11NO3S/c11-9(12)7-1-2-8(14-7)10-3-5-13-6-4-10/h1-2H,3-6H2,(H,11,12)
332345-27-4Relevant articles and documents
Synthesis of new heterocyclic analogs of linezolid
Nguyen, Son T.,Li, Bing,Peet, Norton P.
, p. 6056 - 6058 (2015)
We have previously attempted to prepare 5-(4-morpholinyl)-2-aminothiophene (3) by reducing 5-(4-morpholinyl)-2-nitrothiophene (2), to prepare a precursor for the preparation of thienyloxazolidinones as potential linezolid-like antibiotics. This strategy failed, but allowed us to define an interesting reductive aromatization reaction. We have now succeeded in producing thienyloxazolidinones using an alternative strategy, initiating from 5-(4-morpholinyl)thiophene-2-carboxaldehyde (8). This Letter describes the synthesis of thienyloxazolidinone 14, which is a key intermediate for the preparation of new oxazolidinone antibiotics with a thiophene core.
