332366-39-9

Basic information

• Product Name: 1-benzyloxycarbonyl-6-bromo-4-oxo-4H-quinoline
• Synonyms: 1-benzyloxycarbonyl-6-bromo-4-oxo-4H-quinoline
• CAS NO: 332366-39-9
• Molecular Weight: 358.191
• Mol File: 332366-39-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-benzyloxycarbonyl-6-bromo-4-oxo-4H-quinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 1-benzyloxycarbonyl-6-bromo-4-oxo-4H-quinoline(332366-39-9)
• EPA Substance Registry System: 1-benzyloxycarbonyl-6-bromo-4-oxo-4H-quinoline(332366-39-9)

Safety Data

• Hazardous Substances Data: 332366-39-9(Hazardous Substances Data)

Upstream product

• 501-53-1 benzyl chloroformate 
• 145369-94-4 6-bromo-3-quinolinecarboxylic acid-4-ol 
• 106-40-1 4-bromo-aniline 
• 187278-01-9 5-(((4-bromophenyl)amino)methylene)-2,2-dimethyl-1,3-dioxane-4,6-dione 

Relevant articles and documents

Cu(I)-Catalyzed Alkynylation of Quinolones

Herein we report the first alkynylation of quinolones with terminal alkynes under mild reaction conditions. The reaction is catalyzed by Cu(I) salts in the presence of a Lewis acid, which is essential for the reactivity of the system. The enantioselective version of this transformation has also been explored, and the methodology has been applied in the synthesis of the enantioenriched tetrahydroquinoline alkaloid cuspareine.

Efficient allylation of 4-silyloxyquinolinium triflates and other positively charged heteroaromatic systems

The regioselective allylation of 4-silyloxyquinolinium triflates with allyltri-n-butyltin has been performed to give 2-allyl-4-silyloxy-1,2-dihydroquinolines with excellent yields. Similiar results have been obtained with 4-silyloxy-1-benzopyrylium triflates and 4-silyloxy-1-benzothiopyrylium triflates.