33237-87-5

Basic information

• Product Name: (4-Chloro-phenyl)-indan-2-yl-amine
• CAS NO: 33237-87-5
• Molecular Weight: 243.736
• Mol File: 33237-87-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (4-Chloro-phenyl)-indan-2-yl-amine(CAS DataBase Reference)
• NIST Chemistry Reference: (4-Chloro-phenyl)-indan-2-yl-amine(33237-87-5)
• EPA Substance Registry System: (4-Chloro-phenyl)-indan-2-yl-amine(33237-87-5)

Safety Data

• Hazardous Substances Data: 33237-87-5(Hazardous Substances Data)

Upstream product

• 106-47-8 4-chloro-aniline 
• 17783-69-6 indan-2-yl p-toluenesulphonate 

Relevant articles and documents

Nucleophilic Substitution Reactions of Indan-2-yl Arenesulfonates with Anilines in Methanol

The nucleophilic substitution reactions of (Y)-indan-2-yl (Z)-arenesulfonates with (X)-anilines in methanol at 55.0 deg C are reported.Sign reversals in all three second-order cross-interaction constants, ρXY, ρYZ and ρXZ, are observed at non-interaction points Z = -0.11 (ρXY = 0), X = -0.02 (ρYZ = 0) and Y = 0.43 (ρXZ = 0) respectively, which have been ascribed to an unusually large third-order cross-interaction constant, ρXYZ = -0.53, for the reaction series.An SN2 transition state with a tilted, parallel stacked and displaced structure of the three benzene rings in the nucleophile (X), substrate (Y) and leaving group (Z) is proposed to rationalize the strong three-body coupling manifested by the large ρXYZ value.