33284-09-2

Basic information

• Product Name: Benzenesulfonamide, N-[2-(1H-indol-3-yl)ethyl]-4-nitro-
• CAS NO: 33284-09-2
• Molecular Formula: C16H15N3O4S
• Molecular Weight: 345.379
• Mol File: 33284-09-2.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: Benzenesulfonamide, N-[2-(1H-indol-3-yl)ethyl]-4-nitro-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenesulfonamide, N-[2-(1H-indol-3-yl)ethyl]-4-nitro-(33284-09-2)
• EPA Substance Registry System: Benzenesulfonamide, N-[2-(1H-indol-3-yl)ethyl]-4-nitro-(33284-09-2)

Safety Data

• Hazardous Substances Data: 33284-09-2(Hazardous Substances Data)

Upstream product

• 343-94-2 tryptamine hydochloride 
• 98-74-8 4-Nitrobenzenesulfonyl chloride 
• 61-54-1 tryptamine 

Downstream Products

• 1386416-81-4 C₃₉H₃₄N₆O₈S₂ 
• 1386416-87-0 C₃₉H₃₄N₆O₉S₂ 
• 1386416-85-8 C₄₀H₃₆N₆O₉S₂ 
• 1386416-83-6 C₃₉H₃₄N₆O₉S₂ 
• 1386416-91-6 C₄₀H₃₆N₆O₁₀S₂ 
• 1386416-89-2 C₄₁H₃₈N₆O₁₀S₂ 
• 1386416-93-8 C₄₁H₃₈N₆O₁₁S₂ 

Relevant articles and documents

Chiral bifunctional bisphosphine enabled enantioselective tandem Michael addition of tryptamine-derived oxindoles to ynones

A chiral phosphine-catalyzed tandem Michael addition of tryptamine-derived oxindoles to ynones has been developed, which provides facile access to a series of optically enriched spiro[pyrrolidine-3,3′-oxindole] compounds in good yields with good to excell

Exploration of a KI-catalyzed oxidation system for direct construction of bispyrrolidino[2,3-: B] indolines and the total synthesis of (+)-WIN 64821

A facile and environmentally benign KI(cat.)/NaBO3·4H2O oxidation system has been developed for the tandem oxidative aminocyclization/coupling of tryptamines, affording a series of 3a,3a′-bispyrrolidino[2,3-b]indolines with high efficiency (up to 94% yield). This reaction features an electrophilic "I+" mechanism, which is importantly quite different from and milder than the typical radical-involving process, and can be readily amplified for the total synthesis of (+)-WIN 64821.

Reaction of Donor-Acceptor Cyclobutanes with Indoles: A General Protocol for the Formal Total Synthesis of (±)-Strychnine and the Total Synthesis of (±)-Akuammicine

A ligand-promoted catalytic [4+2] annulation reaction using indole derivatives and donor-acceptor (D-A) cyclobutanes is reported, thus providing an efficient and atom-economical access to versatile cyclohexa-fused indolines with excellent levels of diastereoselectivity and a broad substrate scope. In the presence of a chiral SaBOX ligand, excellent enantioselectivity was realized with up to 94 % ee. This novel synthetic method is applied as a general protocol for the total synthesis of (±)-akuammicine and the formal total synthesis of (±)-strychnine from the same common-core scaffold.