3330-25-4Relevant articles and documents
Miyakado et al.
, p. 143,144 (1978)
Efficient and stable small molecule agonist of v [gamma] 9v delta 2t cells
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Paragraph 0436-0438; 0482-0485; 0492-0494; 0546-0548, (2019/04/30)
The invention relates to a formula (I) compound as an efficient and stable small molecule agonist of v [gamma] 9v delta 2t cells, wherein the groups are defined in the specification and the claims. The present invention also relates to pharmaceutical compositions containing the formula (I) compound and use thereof in the treatment of proliferative diseases.
Preparation method of tiglic aldehyde derivative
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Paragraph 0038-0040, (2018/06/16)
The invention provides a preparation method of a tiglic aldehyde derivative. The preparation method comprises the following step of carrying out catalytic oxidation on an isoamylene derivative represented as the following formula (I) in the presence of a catalyst to produce the tiglic aldehyde derivative represented as the following formula (II), wherein the catalyst is a non-metal oxide, and theR in the formula (I) or the formula (II) is selected from aliphatic hydrocarbyl, aryl, aralkyl, halogens, ester groups, acyloxy, acylamino or alkoxy. The preparation method of the tiglic aldehyde derivative provided by the invention has the characteristics of few reaction step, simple process, cheap and easily available raw materials and the like.