333311-80-1

Basic information

• Product Name: Acetic acid, [[5-[[(4-fluorophenyl)amino]methyl]-4-phenyl-4H-1,2,4-triazol-3-yl]thio]-, ethyl ester
• CAS NO: 333311-80-1
• Molecular Formula: C19H19FN4O2S
• Molecular Weight: 386.45
• Mol File: 333311-80-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Acetic acid, [[5-[[(4-fluorophenyl)amino]methyl]-4-phenyl-4H-1,2,4-triazol-3-yl]thio]-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Acetic acid, [[5-[[(4-fluorophenyl)amino]methyl]-4-phenyl-4H-1,2,4-triazol-3-yl]thio]-, ethyl ester(333311-80-1)
• EPA Substance Registry System: Acetic acid, [[5-[[(4-fluorophenyl)amino]methyl]-4-phenyl-4H-1,2,4-triazol-3-yl]thio]-, ethyl ester(333311-80-1)

Safety Data

• Hazardous Substances Data: 333311-80-1(Hazardous Substances Data)

Upstream product

• 436813-76-2 1-(N-p-fluorophenylamino)acetyl-4-phenyl thiosemicarbazide 
• 103-72-0 phenyl isothiocyanate 
• 710-31-6 2-[(4-fluorophenyl)amino]acetohydrazide 
• 105-39-5 chloroacetic acid ethyl ester 
• 482645-52-3 3-(N-p-fluorophenylamino)methyl-5-mercapto-4-phenyl-1,2,4-triazole 

Downstream Products

• 680594-43-8 [5-(N-p-fluorophenylamino)methyl-4-phenyl-1,2,4-triazol-3-yl]thioglycolylhydrazide 

Relevant articles and documents

Synthesis of some functionalized arylaminomethyl-1,2,4-triazoles, 1,3,4-oxa- and thiadiazoles

Thiosemicarbazides undergo different cyclization reactions to give five membered heterocycles. The product of cyclization depends on the reagent used. This cyclization leads to the formation of 1,3,4-oxadiazole, 1,3,4-thiadiazole and 1,2,4-triazole derivatives. The reaction of thioglycolyl hydrazide derivatives of the 1,2,4-triazole compounds was discussed. The activity against hepatitis B virus (HBV) has been tested.