33334-08-6

Basic information

• Product Name: N-Amino-1H-indazole
• Synonyms: N-Amino-1H-indazole;1-Amino-1H-indazole;1H-Indazole-1-amine;1H-Indazol-1-amine;azaindazole;indazol-1-amine;Indazol-1-ylamine
• CAS NO: 33334-08-6
• Molecular Formula: C₇H₇N₃
• Molecular Weight: 133.15
• Product Categories: pharmacetical
• Mol File: 33334-08-6.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 317.543 °C at 760 mmHg
• Flash Point: 145.845 °C
• Appearance: /
• Density: 1.328 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.697
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: N-Amino-1H-indazole(CAS DataBase Reference)
• NIST Chemistry Reference: N-Amino-1H-indazole(33334-08-6)
• EPA Substance Registry System: N-Amino-1H-indazole(33334-08-6)

Safety Data

• Hazardous Substances Data: 33334-08-6(Hazardous Substances Data)

Usage

General Description

N-Amino-1H-indazole is a chemical compound with the molecular formula C7H7N3. It is an aromatic heterocyclic organic compound notable for its indazole/pharmacore moiety and has potential medicinal significance. Its exact properties may vary based on its formulation or method of synthesis, but it's typically characterized by a pale yellow or off-white powder appearance and is highly soluble in standard organic solvents. While it is used in a variety of research settings, it also presents certain risks, as it may be harmful if swallowed, cause skin and eye irritation, or even cause respiratory irritation. Handling and storage of N-amino-1H-indazole should follow the standard safety protocols for chemicals.

InChI:InChI=1/C7H7N3/c8-10-7-4-2-1-3-6(7)5-9-10/h1-5H,8H2

Upstream product

• 271-44-3 benzimidazole 
• 71-36-3 butan-1-ol 

Downstream Products

• 111042-00-3 Indazol-1-yl-[1-(5-nitro-furan-2-yl)-meth-(E)-ylidene]-amine 
• 253-83-8 1,2,3-benzotriazine 
• 271-44-3 benzimidazole 
• 1613-34-9 2-ethylquinoline 
• 1613-32-7 2-n-Propylquinoline 
• 3295-64-5 1,2,3,4-tetrahydroacridine 
• 1666-96-2 3-phenylquinoline 
• 5661-06-3 2,3-dihydro-1H-cyclopenta[b]quinoline 
• 1531-62-0 2-butyl-3-methylquinoline 
• 243-51-6 11H-indeno[1,2-b]quinoline 
• 97990-19-7 3-Amino-2-methyl-2H-indazol 

Relevant articles and documents

1-[(imidazolidin-2-yl)imino]indazole. Highly α2/I 1 selective agonist: Synthesis, X-ray structure, and biological activity

Novel benzazole derivatives bearing a (imidazolidin-2-yl)imino moiety at position 1 or 2 were synthesized by reacting 1-amino- or 2-aminobenzazoles with N,N′-bis(tert-butoxycarbonyl)imidazolidine-2-thione in the presence of HgCl2. Structures of

1-(3-aminoindazol-5-yl)-3-phenylmethyl-cyclic ureas useful as HIV protease inhibitors

The present invention relates to compounds of formulae I and II: STR1 or pharmaceutically acceptable salt forms or prodrugs thereof, which are useful as inhibitors of HIV protease, and to pharmaceutical compositions and diagnostic kits comprising the same, and methods of using the same for treating viral infection or as an assay standard or reagent.

3-substituted cephem compounds

The present invention relates to novel cephalosporins of the formula (I); STR1 wherein, R1 represents a C1 ?C4 alkyl group or STR2 wherein, R2 and R3, independently, represent hydrogen or a C1 ?C3 alkyl group and R4 represents hydrogen or a C1 ?C4 alkyl group; R1a represents hydrogen or an amino-protecting group; Q represents CH or N; and the formula STR3 represents a saturated or unsaturated heterocyclic group which contains 1 to 4 nitrogen atoms of which one is substituted with an amino group to form quaternary ammonium, and oxygen or sulfur, or a fused heterocyclic group thereof formed together with a substituted or unsubstituted benzene or an optional heterocyclic group, or a pharmaceutically acceptable salt thereof, to processes for preparing the same and to a pharmaceutical composition containing the same as an active ingredient. The compounds(1) according to the invention exhibit potent antibacterial activity and broad antibacterial spectrum against the Gram-positive strains including Staphylococcus as well as Gram-negative strains including Pseudomonas, and, therefore, are expected to be very useful in treatment of various diseases caused by bacterial infection in human beings and animals.