33348-72-0

Basic information

• Product Name: 3-hydroxy-1-(4'-methylphenyl)propan-1-one
• Synonyms: 3-hydroxy-1-(4'-methylphenyl)propan-1-one
• CAS NO: 33348-72-0
• Molecular Weight: 164.204
• Mol File: 33348-72-0.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 3-hydroxy-1-(4'-methylphenyl)propan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-hydroxy-1-(4'-methylphenyl)propan-1-one(33348-72-0)
• EPA Substance Registry System: 3-hydroxy-1-(4'-methylphenyl)propan-1-one(33348-72-0)

Safety Data

• Hazardous Substances Data: 33348-72-0(Hazardous Substances Data)

Upstream product

• 128993-97-5 4-(4'-methylphenyl)-1,3-dioxane 
• 122-00-9 para-methylacetophenone 
• 19832-78-1 1-(4-methylphenyl)prop-2-en-1-one 
• 4294-57-9 para-methylphenylmagnesium bromide 
• 197854-75-4 3-oxo-3-(4-methylphenylpropyl)dimethylvinylsilane 
• 99-75-2 4-methyl-benzoic acid methyl ester 
• 5406-39-3 3-(4-methylphenyl)propanol 
• 40122-37-0 1-(p-tolyl)cyclopropan-1-ol 

Relevant articles and documents

Indium(III)-Catalyzed Hydration and Hydroalkoxylation of α,β-Unsaturated Ketones in Aqueous Media

The hydration of α,β-unsaturated ketones with water proceeded efficiently in the presence of In(OTf)3 (20 mol%) in aqueous media to afford synthetically versatile β-hydroxyketones in moderate to good yields with good functional group compatibility. The method also can be extended to the hydroalkoxylation of α,β-unsaturated ketones with various alcohols for the efficient synthesis of β-alkoxyketones as well as tetrahydrofuran derivatives. (Figure presented.).

Bismuth trichloride-catalyzed oxy-Michael addition of water and alcohol to α,β-unsaturated ketones

An efficient method was developed for the conjugate addition of water to various α,β-unsaturated ketones by using bismuth(III) chloride as a catalyst. The reactions proceeded smoothly in the presence of a catalytic amount of BiCl3 (20 mol%) in aqueous media to furnish a variety of synthetically useful β-hydroxyl ketones in moderate to good yields. Apart from water molecule, various alcohols could also be employed as nucleophiles to react with α,β-unsaturated ketones, leading to β-alkoxyl ketones in modest to high yields. In addition, the mild reaction conditions also entailed the conjugate addition reactions to proceed with the tolerance to a range of functional groups.

Purification and characterization of a (r)-1-phenyl-1, 3-propanediol- producing enzyme from trichosporon fermentans aj-5152 and enzymatic (r)-1-phenyl-1, 3-propanediol production

An (R)-1-phenyl-1, 3-propanediol-producing enzyme was purified from Trichosporon fermentans AJ-5152. It was NADPH-dependent and converted 3-hydroxy-1- phenylpropane-1-one (HPPO) to (R)-1-phenyl-1, 3-propanediol [(R)-PPD] with anti-Prelog's specificity. It