3337-71-1 Usage
Description
Asulam is a sulfonamide herbicide that can be formulated as a sodium salt. It is highly water-soluble and exhibits strong systemic properties, allowing it to be absorbed through foliar and root uptake. Asulam is effective against perennial weeds due to its ability to translocate to underground meristematic organs. It has a chemical structure defined as a carbamate ester with a (4-aminophenyl)sulfonyl group substitution at the nitrogen atom, and it appears as a light brown solid.
Uses
1. Used in Herbicide Applications:
Asulam is used as a carbamate herbicide for controlling the growth of unwanted plants.
2. Used in Folic Acid Biosynthesis Inhibition:
Asulam is used as a folic acid biosynthesis inhibitor, disrupting the growth and development of certain plants.
3. Used in Alfalfa and Uncropped Land:
Asulam is used as a systemic, preand postemergence herbicide for controlling several perennial grasses and specific broad-leaved weeds such as brackenfern, crabgrass, itchgrass, paragrass, tansy ragwort, and wild mustard in alfalfa and uncropped land.
4. Used in Certain Ornamentals and Turf:
Asulam is also utilized as a herbicide in certain ornamental plants and turf to manage unwanted vegetation growth.
Health Hazard
Low order of toxicity; no adverse effect onskin reported; ingestion of large dose couldproduce cholinergic effects.LD50 oral (rat): 2000 mg/kg.
Pharmacology
Asulam-induced
growth inhibition of carrot cell cultures was reversed by
4-aminobenzoic acid (8), and depletion of folate derivatives
in treated plants (7) provides further evidence that
the synthesis of folic acid is the primary target of
asulam. Furthermore, asulam is structurally related to
sulfonilamide and to sulfonamide antimicrobial drugs,
which are competitive inhibitors of 7,8-dihydropteroate
synthase (DHPS) (5,9).
Environmental Fate
Soil. It is not persistent in soils since its half-life is approximately 6–14 days (Hartley
and Kidd, 1987). The short persistence time is affected by soil temperature and moisture
content. The half-life of asulam in a heavy clay soil having a moisture content of 34%
and maintained at 20°C was 7 days (Smith and Walker, 1977). In soil, sulfanilamide was
reported as a product of hydrolysis. In non-sterile soils, this compound further degraded
to unidentifiable products (Smith, 1988) which may include substituted anilines (Bartha,
1971).Photolytic. The reported photolytic half-lives for asulam in water at pH 3 and 9 were
2.5 and 9 days, respectively (Humburg et al., 1989)Chemical/Physical. Forms water-soluble salts (Hartley and Kidd, 1987). When heated
to 75°C, asulam decomposed to sulfanilic acid, carbamic acid and sulfanilamide. At 90°C,
4-nitro- and 4-nitrosobenzene sulfonic acids were released (Rajagopal et a
Check Digit Verification of cas no
The CAS Registry Mumber 3337-71-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,3,3 and 7 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 3337-71:
(6*3)+(5*3)+(4*3)+(3*7)+(2*7)+(1*1)=81
81 % 10 = 1
So 3337-71-1 is a valid CAS Registry Number.
InChI:InChI=1/C8H10N2O4S/c1-14-8(11)10-15(12,13)7-4-2-6(9)3-5-7/h2-5H,9H2,1H3,(H,10,11)
3337-71-1Relevant articles and documents
5,6-Dihydro-1,2,4,6-thiatriazin-5-one-1,1-dioxides
-
, (2008/06/13)
5,6-Dihydro-1,2,4,6-thiatriazin-5-one-1,1-dioxides of the formula STR1 where R1 is hydrogen, a metal atom or an unsubstituted or substituted ammonium radical, R2 is a saturated or unsaturated straight-chain aliphatic radical of up to 10 carbon atoms, a cycloaliphatic radical or 3 to 7 carbon atoms, a branched saturated or unsaturated aliphatic radical of 3 to 10 carbon atoms, a halogen-, alkoxy- or alkylmercapto-substituted aliphatic radical of 2 to 10 carbon atoms tetrahydrofuryl substituted methyl, a cycloalkoxy-substituted aliphatic radical of 4 to 10 carbon atoms, unsubstituted or halogen-substituted benzyl or phenyl, halophenyl, or alkylphenyl of a total of up to 10 carbon atoms, R3 is hydrogen, a straight-chain aliphatic radical of up to 10 carbon atoms, a cycloaliphatic radical of 3 to 7 carbon atoms, a branched aliphatic radical of 3 to 10 carbon atoms, haloalkyl, or alkoxyalkyl of 2 to 10 carbon atoms and X is oxygen and may also be sulfur if R2 is unsubstituted or halogen-substituted benzyl, processes for their preparation, and herbicides containing the above compounds.
