33420-68-7

Basic information

• Product Name: Ethanedione, (4-methoxyphenyl)phenyl-, 2-oxime
• CAS NO: 33420-68-7
• Molecular Formula: C15H13NO3
• Molecular Weight: 255.273
• Mol File: 33420-68-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Ethanedione, (4-methoxyphenyl)phenyl-, 2-oxime(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanedione, (4-methoxyphenyl)phenyl-, 2-oxime(33420-68-7)
• EPA Substance Registry System: Ethanedione, (4-methoxyphenyl)phenyl-, 2-oxime(33420-68-7)

Safety Data

• Hazardous Substances Data: 33420-68-7(Hazardous Substances Data)

Upstream product

• 7647-01-0 hydrogenchloride 
• 103-82-2 phenylacetic acid 
• 1023-17-2 4-methoxyphenyl benzyl ketone 
• 4231-69-0 1-(4-methoxybenzoyl)-1H-1,2,3-benzotriazole 
• 46318-58-5 4-methoxybenzoylnitromethane 
• 71-43-2 benzene 
• 64-17-5 ethanol 
• 32320-41-5 2-(4-methoxyphenyl)-1-nitro-1-phenylethylene 
• 110-46-3 isopentyl nitrite 
• 92664-25-0 α-hydroxyimino-α-(p-methoxyphenyl)acetophenone 
• 22711-21-3 4-methoxybenzil 

Downstream Products

• 22719-00-2 4-methoxy-benzil-α'-seqcis-oxime α-seqtrans-oxime 
• 22719-00-2 4-methoxy-benzil-α-seqcis-oxime α'-seqtrans-oxime 
• 1023-17-2 4-methoxyphenyl benzyl ketone 
• 22719-00-2 (E,E)-4-methoxy-benzil dioxime 
• 22719-00-2 4-methoxy-benzil dioxime 
• 69367-05-1 6-(4-methoxy-phenyl)-5-phenyl-2H-[1,2,4]triazine-3-thione 
• 7099-91-4 p-methoxybenzoylformic acid 
• 100-09-4 4-methoxybenzoic acid 
• 33420-69-8 α-amino-4-methoxy-deoxybenzoin 
• 121612-15-5 (4-Methoxy-phenyl)-phenyl-furazan 

Relevant articles and documents

Synthesis and neuroprotective activity of novel 1,2,4-triazine derivatives with ethyl acetate moiety against H2O2 and Aβ-induced neurotoxicity

A series of 5,6-diaryl-1,2,4-triazine-3-thioacetate derivatives 3a–f, 8a–d and their regioisomer 8e were synthesized. Neuroprotective activity of compounds was assessed against H2O2 and β-amyloid-induced toxicity in PC12 and SH-SY5Y cells respectively. Surprisingly, ethyl 2-(5-(4-chlorophenyl)-6-(4-methoxyphenyl)-3-thioxo-1,2,4-triazin-2(3H)-yl)acetate (8e) was the most potent compound in both tests with EC50 of 14 μM in H2O2 induced apoptosis and also could increase 40% of cell viability revealed by cytometric analysis with Annexin V/PI staining. It was also shown that regioisomer 8e has more neuroprotective activity than Quercetin in β-amyloid induced toxicity. Morphologic evaluation of cells by DAPI staining and TUNEL assay showed the effectiveness of this compound to improve neurite outgrowth in neuronal cells.