334476-87-8Relevant articles and documents
Synthesis of Chiral Piperazines via Hydrogenation of Pyrazines Activated by Alkyl Halides
Huang, Wen-Xue,Liu, Lian-Jin,Wu, Bo,Feng, Guang-Shou,Wang, Baomin,Zhou, Yong-Gui
supporting information, p. 3082 - 3085 (2016/07/13)
A facile method has been developed for the synthesis of chiral piperazines through Ir-catalyzed hydrogenation of pyrazines activated by alkyl halides, giving a wide range of chiral piperazines including 3-substituted as well as 2,3- and 3,5-disubstituted