3351-86-8 Usage
Description
Fucoxanthin is a naturally occurring xanthophyll carotenoid pigment that is predominantly found in brown algae and oceanic microalgae. It is the second-most abundant carotenoid on Earth after β-carotene and is known for its various beneficial physiological activities, including anti-tumor, anti-inflammatory, anti-oxidant, and anti-obesity effects. Fucoxanthin is an orange-colored pigment that is insoluble in water but soluble in organic solvents such as ethanol.
Uses
Used in Pharmaceutical Applications:
Fucoxanthin is used as an anti-obesity, anticancer, anti-cholesterol, and anti-diabetic agent due to its various pharmaceutical effects. It has been shown to possess anti-angiogenic, hepatoprotective, cardiovascular, and cerebrovascular protective properties. It stimulates G1 cell-cycle arrest and apoptosis in cancer cell lines.
Used in Food Industry:
Fucoxanthin is used as a food colorant due to its orange-colored pigment. However, it is important to note that it is very unstable and can be easily affected by heating, aerial exposure, and illumination.
Used in Skin Care and Beauty Industry:
Fucoxanthin is used in the skin care and beauty industry for its anti-inflammatory and anti-oxidant properties, which can contribute to the health and appearance of the skin.
Used in Food Supplements Market:
Fucoxanthin is widely used in the food supplements market for its various health benefits, including its protective effects on nerve cells and its ability to increase the content of arachidonic acid (ARA) and docosahexaenoic acid (DHA) in mice.
Used in Neuroprotective Studies:
Fucoxanthin has been used to study its neuroprotective effects, which can be beneficial for the development of treatments for neurological disorders.
Used in Microalgae Strain Identification:
Fucoxanthin has been used in calibration to identify the most efficient fucoxanthin-producing strains of microalgae, which can be important for optimizing the production of this beneficial compound.
Biochem/physiol Actions
Xanthophyll carotenoid pigment extracted from algae. Exhibits anticancer, antioxidant, anti-obesity and anti-inflammatory properties.
Check Digit Verification of cas no
The CAS Registry Mumber 3351-86-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,3,5 and 1 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 3351-86:
(6*3)+(5*3)+(4*5)+(3*1)+(2*8)+(1*6)=78
78 % 10 = 8
So 3351-86-8 is a valid CAS Registry Number.
InChI:InChI=1/C42H60O7/c1-29(18-14-19-31(3)22-23-37-38(6,7)26-35(49-33(5)43)27-40(37,10)46)16-12-13-17-30(2)20-15-21-32(4)36(45)28-42(48)39(8,9)24-34(44)25-41(42,11)47/h12-22,34-35,44,46-48H,24-28H2,1-11H3/b13-12+,18-14+,20-15+,29-16+,30-17+,31-19+,32-21+/t23-,34-,35-,40+,41+,42-/m0/s1
3351-86-8Relevant articles and documents
Application of diphenyl diselenide as a new catalyst for photochemical stereoisomerization of carotenoids
Strand, Aase,Liaaen-Jensen, Synnove
, p. 1263 - 1269 (2007/10/03)
In a comparative study, diphenyl diselenide was shown to be an alternative to iodine as a catalyst for photochemical E/Z isomerization of carotenoids. Suitable conditions for the stereomutation of zeaxanthin, violaxanthin, canlhaxanthin and fucoxanthin are reported. Photochemical allenic isomerization with increased R to S conversion was achieved by employing diphenyl diselenide rather than iodine as the catalyst. Reproducible and expedient artificial light conditions, avoiding insolation (sunlight), are reported. Diphenyl diselenide tolerated the presence of Huenig's base upon stereoisomerization of acid-sensitive carotenoids. Diphenyl ditelluride effected E/Z stereomutation, but no allenic R/S isomerization of fucoxanthin. The presence of base decreased the isomerization rate in the absence of catalyst and may serve to decrease undesirable E/Z stereoisomerization of base-stable carotenoids. Acta Chemica Scandinavica 1998.
Total synthesis of photosynthetic pigment fucoxanthin by use of oxo- metallic catalyst
Yamano,Ito
, p. 410 - 412 (2007/10/02)
The first total synthesis of optically active fucoxanthin 1 has been accomplished via the 8-oxo-compound 7, efficiently prepared by rearrangement of the α-acetylenic alcohol 2 using oxo-metallic catalyst and subsequent iodine catalyzed double bond-shift.
