335254-75-6Relevant articles and documents
Design, Synthesis, and Blood-Brain Barrier Transport Study of Pyrilamine Derivatives as Histone Deacetylase Inhibitors
Hiranaka, Seiya,Tega, Yuma,Higuchi, Kei,Kurosawa, Toshiki,Deguchi, Yoshiharu,Arata, Mayumi,Ito, Akihiro,Yoshida, Minoru,Nagaoka, Yasuo,Sumiyoshi, Takaaki
supporting information, p. 884 - 888 (2018/09/12)
We designed and synthesized a pyrilamine derivative 1 as a selective class I HDAC inhibitor that targets pyrilamine-sensitive proton-coupled organic cation antiporter (PYSOCA) at the blood-brain barrier (BBB). Introduction of pyrilamine moiety to benzamid
Glutamate receptor antagonists
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, (2008/06/13)
The present invention is a compound of formula wherein X is an ethynediyl group, R1, R2and R3are as defined in the specification.