335321-15-8

Basic information

• Product Name: (S)-2-((E)-(S)-1-Allyl-non-2-enylamino)-2-phenyl-ethanol
• Synonyms: (S)-2-((E)-(S)-1-Allyl-non-2-enylamino)-2-phenyl-ethanol
• CAS NO: 335321-15-8
• Molecular Weight: 301.472
• Mol File: 335321-15-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-2-((E)-(S)-1-Allyl-non-2-enylamino)-2-phenyl-ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-((E)-(S)-1-Allyl-non-2-enylamino)-2-phenyl-ethanol(335321-15-8)
• EPA Substance Registry System: (S)-2-((E)-(S)-1-Allyl-non-2-enylamino)-2-phenyl-ethanol(335321-15-8)

Safety Data

• Hazardous Substances Data: 335321-15-8(Hazardous Substances Data)

Upstream product

• 18829-56-6 (E)-2-Nonenal 
• 20989-17-7 (2S)-2-phenylglycinol 
• 2622-05-1 allylmagnesium bromide 

Downstream Products

• 335321-23-8 (S)-2-[Allyl-((E)-(S)-1-allyl-non-2-enyl)-amino]-2-phenyl-ethanol 

Relevant articles and documents

Enantioselective synthesis of 2-substituted-N-Boc-Δ-4,5-piperidines

The title compounds were prepared through a synthetic sequence involving: (i) a reaction of the condensation product between an enantiopure β-amino alcohol and an aldehyde with allylmagnesium chloride; (ii) an N-allylation of the resulting secondary amine; (iii) a chemoselective cleavage of the β-amino alcohol residue; and (iv) a protection of the secondary amine followed by a ring closing metathesis. The advantageous use of (1R,2S)-norephedrine was demonstrated in these syntheses.