3356-92-1 Usage
General Description
5-bromo-3-phenyl-oxazole is a chemical compound that belongs to the oxazole family. It is an organic compound with the molecular formula C9H6BrNO and a molar mass of 218.05 g/mol. 5-bromo-3-phenyl-oxazole is characterized by a five-membered aromatic ring containing an oxygen and a nitrogen atom. The presence of a bromine atom and a phenyl group in the structure gives 5-bromo-3-phenyl-oxazole its unique properties and reactivity. It is commonly used as a building block in organic synthesis and medicinal chemistry, where it serves as a precursor for the synthesis of various pharmaceutical compounds and biologically active molecules. The compound has potential applications in drug discovery, agrochemicals, and material science due to its diverse chemical reactivity and structural properties.
Check Digit Verification of cas no
The CAS Registry Mumber 3356-92-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,3,5 and 6 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 3356-92:
(6*3)+(5*3)+(4*5)+(3*6)+(2*9)+(1*2)=91
91 % 10 = 1
So 3356-92-1 is a valid CAS Registry Number.
InChI:InChI=1/C9H6BrNO/c10-9-6-8(11-12-9)7-4-2-1-3-5-7/h1-6H
3356-92-1Relevant articles and documents
General Platform for the Conversion of Isoxazol-5-ones to 3,5-Disubstituted Isoxazoles via Nucleophilic Substitutions and Palladium Catalyzed Cross-Coupling Strategies
Fernandes, Alessandra A. G.,da Silva, Amanda F.,Okada, Celso Y.,Suzukawa, Vitor,Cormanich, Rodrigo A.,Jurberg, Igor D.
, p. 3022 - 3034 (2019/05/17)
A general platform for the conversion of isoxazol-5-ones to 3,5-disubstituted isoxazoles has been developed via a two-step strategy. The first step leads to the formation of 5-(pseudo)halogenated isoxazoles, while in the second, a variety of heteroalkyl-, heteroaryl-, alkyl-, alkenyl-, alkynyl- and aryl-chains can be installed via nucleophilic substitutions or palladium catalyzed cross-coupling reactions.
Nitrosation of 2-aryl-1,1-dibromocyclopropanes: Synthesis of 3-aryl-5-bromoisoxazoles
Bondarenko, Oksana B.,Vinogradov, Aleksandr A.,Danilov, Pavel A.,Nikolaeva, Svetlana N.,Gavrilova, Anna Yu.,Zyk, Nikolai V.
, p. 6577 - 6579 (2015/11/09)
An efficient transformation of 2-aryl-1,1-dibromocyclopropanes under the action of sulfur trioxide activated nitrosyl chloride has been developed, providing a series of arylated 5-bromoisoxazoles with good yields. It is noteworthy that under the reported
