335672-28-1Relevant articles and documents
Preparation method of arylamine o-substituted compound
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Paragraph 0083-0085, (2019/11/13)
The invention discloses a preparation method of an arylamine o-substituted compound as shown in a formula I in the specification. The preparation method provided by the invention comprises the following steps: (1) in a continuous flow reactor, carrying ou
Rational design of central selective acetylcholinesterase inhibitors by means of a "bio-oxidisable prodrug" strategy
Bohn, Pierre,Le Fur, Nicolas,Hagues, Guillaume,Costentin, Jean,Torquet, Nicolas,Papamicael, Cyril,Marsais, Francis,Levacher, Vincent
experimental part, p. 2612 - 2618 (2009/10/30)
This work deals with the design of a "bio-oxidisable prodrug" strategy for the development of new central selective acetylcholinesterase inhibitors. This prodrug approach is expected to reduce peripheral anticholinesterase activity responsible for various
