33577-96-7Relevant articles and documents
Mechanistic Divergence in the Hydrogenative Synthesis of Furans and Butenolides: Ruthenium Carbenes Formed by gem-Hydrogenation or through Carbophilic Activation of Alkynes
Peil, Sebastian,Fürstner, Alois
supporting information, p. 18476 - 18481 (2019/11/14)
Enynes with a tethered carbonyl substituent are converted into substituted furan derivatives upon hydrogenation using [Cp*RuCl]4 as the catalyst. Paradoxically, this transformation can occur along two distinct pathways, each of which proceeds via discrete pianostool ruthenium carbenes. In the first case, hydrogenation and carbene formation are synchronized (“gem-hydrogenation”), whereas the second pathway comprises carbene formation by carbophilic activation of the triple bond, followed by hydrogenative catalyst recycling. Representative carbene intermediates of either route were characterized by X-ray crystallography; the structural data prove that the attack of the carbonyl group on the electrophilic carbene center follows a Bürgi–Dunitz trajectory.
Photophysical and theoretical studies of diphenylacetylene derivatives with restricted rotation
Szyszkowska, Ma?gorzata,Czaplewski, Cezary,Wiczk, Wies?aw
, p. 81 - 89 (2017/03/11)
Diphenylacetylene derivatives containing electron-donor (amino) and electron-acceptor (ester) groups in 2,2′ or 3,2′ positions in phenyl rings were synthesized to study the effects of intramolecular charge transfer and stiffening of the conformation by in
Base-catalyzed heterocyclization of 2-(R-ethynyl)benzohydroxamic acids
Vasilevskii,Mikhailovskaya,Stepanov,Mamatyuk,Fadeev
, p. 506 - 509 (2014/06/10)
Sonogashira alkynylation of methyl 2-iodobenzoate with terminal acetylenes gave a series of methyl 2-(alk-1-yn-1-yl)benzoates which reacted with hydroxylamine in boiling methanol to produce five- or six-membered N-hydroxy lactams, 3-R-methylidene-2-hydroxy-2,3-dihydroisoindol-1-ones or 3-R-isoquinolin-1(2H)-ones, depending on the acetylenic substituent nature.
