336783-63-2

Basic information

• Product Name: 4,6-dichloro-3-[2-cyano-2-(4-methoxy-phenyl)-vinyl]-1H-indole-2-carboxylic acid ethyl ester
• CAS NO: 336783-63-2
• Molecular Weight: 415.276
• Mol File: 336783-63-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4,6-dichloro-3-[2-cyano-2-(4-methoxy-phenyl)-vinyl]-1H-indole-2-carboxylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4,6-dichloro-3-[2-cyano-2-(4-methoxy-phenyl)-vinyl]-1H-indole-2-carboxylic acid ethyl ester(336783-63-2)
• EPA Substance Registry System: 4,6-dichloro-3-[2-cyano-2-(4-methoxy-phenyl)-vinyl]-1H-indole-2-carboxylic acid ethyl ester(336783-63-2)

Safety Data

• Hazardous Substances Data: 336783-63-2(Hazardous Substances Data)

Upstream product

• 53995-82-7 4,6-dichloro-indole-2-carboxylic acid,ethyl ester 
• 104-47-2 p-methoxybenzylnitrile 
• 153435-96-2 ethyl-3-formyl-4,6-dichloro-indole-2-carboxylate 

Downstream Products

• 336783-66-5 3-[2-carbamoyl-2-(4-methoxy-phenyl)-vinyl]-4,6-dichloro-1H-indole-2-carboxylic acid ethyl ester 

Relevant articles and documents

Synthesis of (E)-3-(2-carboxy-2-pyridyl-vinyl)-4,6-dichloro-1H-indole-2-carboxylic acids, glycine-site NMDA receptor antagonists, utilizing the Knoevenagel condensation reaction

The Knoevenagel condensation of arylacetonitriles with ethyl 4,6-dichloro-3-formyl-1H-indole-2-carboxylate (2), followed by hydrolysis, provides a convenient entry into a series of analogs of MDL 105,519, 1, a selective glycine site N-methyl-D-aspartate (