33708-60-0

Basic information

• Product Name: (2E)-1-(4-methoxybenzyl)-2-(4-methoxybenzylidene)hydrazine
• CAS NO: 33708-60-0
• Molecular Formula: C₁₆H₁₈N₂O₂
• Molecular Weight: 270.3263
• Mol File: 33708-60-0.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 436.087°C at 760 mmHg
• Flash Point: 217.538°C
• Density: 1.065g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.54
• CAS DataBase Reference: (2E)-1-(4-methoxybenzyl)-2-(4-methoxybenzylidene)hydrazine(CAS DataBase Reference)
• NIST Chemistry Reference: (2E)-1-(4-methoxybenzyl)-2-(4-methoxybenzylidene)hydrazine(33708-60-0)
• EPA Substance Registry System: (2E)-1-(4-methoxybenzyl)-2-(4-methoxybenzylidene)hydrazine(33708-60-0)

Safety Data

• Hazardous Substances Data: 33708-60-0(Hazardous Substances Data)

Usage

General Description

The chemical compound (2E)-1-(4-methoxybenzyl)-2-(4-methoxybenzylidene)hydrazine, also known by its IUPAC name (E)-N-(4-methoxybenzylidene)-2-(4-methoxyphenyl)hydrazine, is a hydrazine derivative with two functional groups - a hydrazine and a benzylidene. It is commonly used in organic synthesis and pharmaceutical research as a building block in the production of various pharmaceutical compounds. (2E)-1-(4-methoxybenzyl)-2-(4-methoxybenzylidene)hydrazine has potential pharmaceutical applications due to its ability to interact with biological systems, and its synthesis and properties have been studied for potential medicinal applications. The presence of both the benzyl and methoxy functional groups give this compound its unique chemical properties and potential for use in drug development and other chemical applications.

Upstream product

• 3395-77-5 bis-(4-methoxy-benzyl)-diazene 
• 64-17-5 ethanol 
• 81104-53-2 N,N'-bis-(4-methoxy-benzyl)-hydrazine 
• 123-11-5 4-methoxy-benzaldehyde 
• 140-69-2 4-methoxybenzylhydrazine 
• 824-94-2 p-methoxybenzyl chloride 

Downstream Products

• 140-69-2 4-methoxybenzylhydrazine 
• 847-39-2 2,5-bis(4-methoxyphenyl)-1,3,4-oxadiazole 
• 2299-73-2 N,N-bis(4-methoxybenzylidene)hydrazine 

Relevant articles and documents

Metal-Free Synthesis of 1,3,4-Oxadiazoles from N′-(Arylmethyl)hydrazides or 1-(Arylmethyl)-2-(arylmethylene)hydrazines

An efficient and versatile metal-free synthesis of 1,3,4-oxadiazoles from N′-(arylmethyl)hydrazides or 1-(arylmethyl)-2-(arylmethylene)hydrazines through oxidative dehydrogenation is reported. A range of 2,5-disubstituted 1,3,4-oxadiazoles were prepared by treating N′-(arylmethyl)hydrazides with (diacetoxyiodo)benzene in acetonitrile or by treating 1-(arylmethyl)-2-(arylmethylene)hydrazines with [bis(trifluoroacetoxy)iodo]benzene in methyl tert-butyl ether. Aldehyde N-acylhydrazones and aldazines were initially generated in situ as intermediates.