33720-29-5Relevant articles and documents
Catalyst-Free and Transition-Metal-Free Approach to 1,2-Diketones via Aerobic Alkyne Oxidation
Shen, Duyi,Wang, Hongyan,Zheng, Yanan,Zhu, Xinjing,Gong, Peiwei,Wang, Bin,You, Jinmao,Zhao, Yulei,Chao, Mianran
, p. 5354 - 5361 (2021/05/05)
A catalyst-free and transition-metal-free method for the synthesis of 1,2-diketones from aerobic alkyne oxidation was reported. The oxidation of various internal alkynes, especially more challenging aryl-alkyl acetylenes, proceeded smoothly with inexpensive, easily handled, and commercially available potassium persulfate and an ambient air balloon, achieving the corresponding 1,2-diketones with up to 85% yields. Meanwhile, mechanistic studies indicated a radical process, and the two oxygen atoms in the 1,2-diketons were most likely from persulfate salts and molecular oxygen, respectively, rather than water.
Synthetic method of 1,2-diketone compound
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Paragraph 0051-0054, (2018/06/14)
The invention discloses a synthetic method of a 1,2-diketone compound. The method comprises the following steps: under room temperature, an alkyne compound is taken as a raw material, a Ru/C is takenas a catalyst, an oxidizing agent and sulfuric acid are added, acetonitrile and water with a volume ratio being 1-5:1 are taken as solvents, the materials are completely reacted at the temperature of20-30 DEG C, and a reaction solution is subjected to separating and purifying to obtain the 1,2-diketone compound. The method has the advantages that operation is simple, reaction time is short, yield(achieving to 100%) is high, substrate universality is wide, water and acetonitrile are taken as the primary solvents (the solvent acetonitrile is easily recovered and used), and a heterogeneous phase catalyst Ru/C is easily recovered. The synthetic method of the 1,2-diketone compound accords with green chemistry characteristic, and is very suitable for industrialization.
A Desulfonylative Approach in Oxidative Gold Catalysis: Regiospecific Access to Donor-Substituted Acyl Gold Carbenes
Chen, Hongyi,Zhang, Liming
, p. 11775 - 11779 (2015/10/05)
Donor-substituted acyl gold carbenes are challenging to access selectively by gold-promoted intermolecular oxidation of internal alkynes as the opposite regioisomers frequently predominate. By using alkynyl sulfones or sulfonates as substrates, the oxidative gold catalysis in the presence of substituted pyridine N-oxides offers regiospecific access to acyl/aryl, acyl/alkenyl, and acyl/alkoxy gold carbenes by in situ expulsion of sulfur dioxide. The intermediacies of these reactive species are established by their reactivities, including undergoing further oxidation by the same oxidant, cyclopropanation of styrenes, engaging in a [3+2] cycloaddition with α-methylstyrene, and conversion into dienones. Accept it: A desulfonylative approach was developed to regiospecifically access these underexplored acyl gold carbenes from either alkynyl aryl/alkenyl sulfones or alkynyl sulfonate substrates. The reactivities of these donor- and acceptor-substituted carbenes are examined.
