3373-86-2

Basic information

• Product Name: 2-nitrophenyl dimethylcarbamate
• Synonyms: 2-nitrophenyl dimethylcarbamate;Dimethylcarbamic acid o-nitrophenyl ester;N,N-Dimethylcarbamic acid 2-nitrophenyl ester
• CAS NO: 3373-86-2
• Molecular Formula: C₉H₁₀N₂O₄
• Molecular Weight: 0
• Mol File: 3373-86-2.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 321.5°Cat760mmHg
• Flash Point: 148.2°C
• Appearance: /
• Density: 1.292g/cm³
• Vapor Pressure: 0.000296mmHg at 25°C
• Refractive Index: 1.558
• CAS DataBase Reference: 2-nitrophenyl dimethylcarbamate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-nitrophenyl dimethylcarbamate(3373-86-2)
• EPA Substance Registry System: 2-nitrophenyl dimethylcarbamate(3373-86-2)

Safety Data

• Hazardous Substances Data: 3373-86-2(Hazardous Substances Data)

Usage

InChI:InChI=1/C9H10N2O4/c1-10(2)9(12)15-8-6-4-3-5-7(8)11(13)14/h3-6H,1-2H3

Upstream product

• 88-75-5 2-hydroxynitrobenzene 
• 79-44-7 N,N-Dimethylcarbamoyl chloride 
• 68-12-2 N,N-dimethyl-formamide 

Relevant articles and documents

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4-(N,N -dimethylamino)pyridine hydrochloride as a recyclable catalyst for acylation of inert alcohols: Substrate scope and reaction mechanism

4-(N,N-Dimethylamino)pyridine hydrochloride (DMAP·HCl), a DMAP salt with the simplest structure, was used as a recyclable catalyst for the acylation of inert alcohols and phenols under base-free conditions. The reaction mechanism was investigated in detail for the first time; DMAP·HCl and the acylating reagent directly formed N-acyl-4-(N′,N′-dimethylamino) pyridine chloride, which was attacked by the nucleophilic substrate to form a transient intermediate that released the acylation product and regenerated the DMAP·HCl catalyst.

PROCESS FOR PREPARATION OF HIGHLY PURE 3-DIMETHYLAMINOPHENYL DIMETHYLCARBAMATE

The invention discloses a novel process for preparation of highly pure 3-dimethylaminophenyl dimethylcarbamate via formation of aryl dimethylcarbamate which can be easily obtained from diaryl carbonate and dimethylamine.