337378-45-7

Basic information

• Product Name: 5-Pyrimidinecarboxylic acid, 4-(4-chlorophenyl)-1,4-dihydro-6-methyl-2-(methylthio)-, ethyl ester
• CAS NO: 337378-45-7
• Molecular Formula: C15H17ClN2O2S
• Molecular Weight: 324.831
• Mol File: 337378-45-7.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 5-Pyrimidinecarboxylic acid, 4-(4-chlorophenyl)-1,4-dihydro-6-methyl-2-(methylthio)-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Pyrimidinecarboxylic acid, 4-(4-chlorophenyl)-1,4-dihydro-6-methyl-2-(methylthio)-, ethyl ester(337378-45-7)
• EPA Substance Registry System: 5-Pyrimidinecarboxylic acid, 4-(4-chlorophenyl)-1,4-dihydro-6-methyl-2-(methylthio)-, ethyl ester(337378-45-7)

Safety Data

• Hazardous Substances Data: 337378-45-7(Hazardous Substances Data)

Upstream product

• 141-97-9 ethyl acetoacetate 
• 104-88-1 4-chlorobenzaldehyde 
• 14527-26-5 2-methylisothiourea sulphate 
• 154866-92-9 ethyl 4-(4-chlorophenyl)-1,2,3,4-tetrahydro-6-methyl-2-thioxopyrimidine-5-carboxylate 
• 74-88-4 methyl iodide 
• 77-78-1 dimethyl sulfate 

Downstream Products

• 1236204-35-5 ethyl 4-(4-chlorophenyl)-6-methyl-2-(methylthio)pyrimidine-5-carboxylate 
• 1476039-79-8 ethyl 4-(4-chlorophenyl)-2-(dimethylamino)-6-methyl-1,4-dihydropyrimidine-5-carboxylate 
• 1412900-79-8 ethyl 3-(5-bromo-benzofuran-2-carbonyl)-5-(4-chlorophenyl)-7-methyl-1-phenyl-1,5-dihydro-[1,2,4]triazolo[4,3-a]pyrimidine-6-carboxylate 
• 1117816-31-5 C₃₀H₂₂Cl₂N₄O₄ 

Relevant articles and documents

Synthesis, molecular docking, and cardioprotective activity of 2-methylthio-1,4-dihydropyrimidines

A series of 2-methylthio-1,4-dihydropyrimidine derivatives (IIa-IIl) were synthesized in good yields by alkylation of 1,2,3,4-tetrahydropyrimidines (Ia-Il) with methyl iodide in the presence of pyridine. Their structures were confirmed by elemental analys

Mild and efficient oxidative aromatization of 4-substituted-1,4- dihydropyrimidines using (diacetoxyiodo)benzene

(Chemical Equation Presented) 4-Alkyl or aryl-1,4-dihydropyrimidines were readily oxidized by (diacetoxyiodo)benzene under mild reaction conditions to the corresponding pyrimidine derivatives in good to excellent yields.