33744-19-3

Basic information

• Product Name: 2-propylisonicotinonitrile
• Synonyms: 2-propylisonicotinonitrile;4-CYANO-2-PROPYLPYRIDINE;2-Propyl-4-pyridinecarbonitrile;2-propylisonicotinonitrile(SALTDATA: FREE);4-Pyridinecarbonitrile, 2-propyl-;2-propylpyridine-4-carbonitrile;MFCD09834373
• CAS NO: 33744-19-3
• Molecular Formula: C₉H₁₀N₂
• Molecular Weight: 146.1891
• EINECS: 251-665-0
• Mol File: 33744-19-3.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 230°Cat760mmHg
• Flash Point: 91.8°C
• Appearance: /
• Density: 1.02g/cm³
• Vapor Pressure: 0.0673mmHg at 25°C
• Refractive Index: 1.517
• PKA: 2.60±0.10(Predicted)
• CAS DataBase Reference: 2-propylisonicotinonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-propylisonicotinonitrile(33744-19-3)
• EPA Substance Registry System: 2-propylisonicotinonitrile(33744-19-3)

Safety Data

• Hazardous Substances Data: 33744-19-3(Hazardous Substances Data)

Usage

Uses

Derivatives of 2-Propylisonicotinonitrile as HIV-1 protease inhibitors.

InChI:InChI=1/C9H10N2/c1-2-3-9-6-8(7-10)4-5-11-9/h4-6H,2-3H2,1H3

Upstream product

• 80944-48-5 2-propylpyridine-4-carboxamide 
• 1531-17-5 ethyl 2-propylisonicotinate 
• 100129-70-2 2-chloro-6-propyl-isonicotinic acid ethyl ester 
• 100-48-1 pyridine-4-carbonitrile 
• 107-92-6 butyric acid 
• 760-78-1 2-aminopentanoic acid 

Downstream Products

• 14222-60-7 prothionamide 
• 57663-82-8 2-propylisonicotinic acid 
• 172294-74-5 2-propylpyridine-4-carbaldehyde 
• 1046045-61-7 N-(4-(2-(2-propylpyridin-4-yl)thiazol-4-yl)phenyl)methanesulfonamide 
• 125256-02-2 4-(4-chlorophenyl)-2-(propylpyridin-4-yl)thiazole 
• 125255-99-4 4-phenyl-2-(2-propylpyridin-4-yl)thiazole 
• 125256-00-0 2-(2-propylpyridin-4-yl)-4-p-tolylthiazole 
• 893768-43-9 4-(4-fluorophenyl)-2-(2-propylpyridin-4-yl)thiazole 
• 125256-01-1 4-(4-methoxyphenyl)-2-(2-propylpyridin-4-yl)thiazole 
• 920451-09-8 4-(3-methoxyphenyl)-2-(2-propylpyridin-4-yl)thiazole 
• 921119-27-9 4-(2-methoxyphenyl)-2-(2-propylpyridin-4-yl)thiazole 

Relevant articles and documents

Unprotected Amino Acids as Stable Radical Precursors for Heterocycle C-H Functionalization

An efficient and general method for the C-H alkylation of heteroarenes using unprotected amino acids as stable alkyl radical precursors is reported. This one-pot procedure is performed open to air under aqueous conditions and is effective for several natural and unnatural amino acids. Heterocycles of varying structure are suitably functionalized, and reactivity trends reflect the nucleophilic character of the radical species generated.