337519-67-2Relevant articles and documents
Discovery of R-142086 as a factor Xa (FXa) inhibitor: Syntheses and structure-activity relationships of cinnamyl derivatives1,2
Noguchi, Tetsuji,Tanaka, Naoki,Nishimata, Toyoki,Goto, Riki,Hayakawa, Miho,Sugidachi, Atsuhiro,Ogawa, Taketoshi,Niitsu, Yoichi,Asai, Fumitoshi,Ishizuka, Tomoko,Fujimoto, Koichi
experimental part, p. 22 - 33 (2009/08/07)
To develop a novel and effective anticoagulant with potent and selective factor Xa (FXa) inhibitory activity, a new series of cinnamyl derivatives with enhanced lipophilicity and prodrug forms were synthesized and their biological activities were evaluate
