338-70-5

Basic information

• Product Name: 2-hydroxy-2-oxoacetate
• Synonyms: 2-hydroxy-2-oxoacetate;Hydrogen Oxalate;2-Hydroxy-1-oxylato-1,2-ethanedione;2-Oxo-2-hydroxyacetate;Carboxylatoformic acid;oxalate(2-);(3-hydroxy-8-oxabicyclo[3.2.1]oct-6-en-5-yl)methyl-methylazanium;(3-hydroxy-1-methyl-8-oxabicyclo[3.2.1]oct-6-en-5-yl)methyl-methylazanium
• CAS NO: 338-70-5
• Molecular Formula: C₂O₄
• Molecular Weight: 0
• Mol File: 338-70-5.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 365.1°Cat760mmHg
• Flash Point: 188.8°C
• Appearance: /
• Density: g/cm³
• CAS DataBase Reference: 2-hydroxy-2-oxoacetate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-hydroxy-2-oxoacetate(338-70-5)
• EPA Substance Registry System: 2-hydroxy-2-oxoacetate(338-70-5)

Safety Data

• Hazardous Substances Data: 338-70-5(Hazardous Substances Data)

Usage

Description

2-Hydroxy-2-oxoacetate, also known as glycerate, is a dicarboxylic acid dianion obtained by deprotonation of both carboxy groups of oxalic acid. It is an important intermediate in various metabolic pathways and plays a crucial role in energy metabolism.

Uses

Used in Pharmaceutical Industry:
2-Hydroxy-2-oxoacetate is used as a pharmaceutical intermediate for the synthesis of various drugs and pharmaceutical compounds. Its unique chemical structure allows it to be easily modified and incorporated into a wide range of drug molecules.
Used in Cosmetic Industry:
2-Hydroxy-2-oxoacetate is used as a humectant in cosmetics and personal care products. Its ability to attract and retain moisture makes it an effective ingredient in moisturizers, creams, and lotions, helping to maintain skin hydration and elasticity.
Used in Food Industry:
2-Hydroxy-2-oxoacetate is used as a flavor enhancer and preservative in the food industry. Its ability to bind with other molecules and alter their taste and texture properties makes it a valuable ingredient in various food products.
Used in Chemical Industry:
2-Hydroxy-2-oxoacetate is used as a building block in the synthesis of various organic compounds and polymers. Its versatile chemical properties make it a valuable starting material for the production of a wide range of chemical products.
Used in Biotechnology Industry:
2-Hydroxy-2-oxoacetate is used as a substrate in various biotechnological processes, such as the production of biofuels and bioplastics. Its ability to be metabolized by microorganisms makes it a promising feedstock for the development of sustainable and eco-friendly products.

Upstream product

• 100-02-7 4-nitro-phenol 
• 124-38-9 carbon dioxide 
• 19471-65-9 [Ru(NH₃)5(pyrazine)]⁽²⁺⁾ 
• 15843-43-3 silver oxalate 
• 75847-14-2 V⁽³⁺⁾*C₂O₄^(2-)={V(C₂O₄)}⁽¹⁺⁾ 
• 87331-61-1 aquo nitrosyldihydroxo oxalato rhenic acid 
• 56-81-5 glycerol 

Downstream Products

• 124-38-9 carbon dioxide 
• 10097-32-2 bromide 
• 7440-44-0 pyrographite 
• 547-66-0 magnesium(II) oxalate 
• 516-02-9 barium oxalate 
• 144-62-7 oxalic acid 
• 14808-79-8 Sulfate 
• 6047-25-2 iron(II) oxalate dihydrate 
• 814-88-0 cadmium(II) oxalate 
• 547-67-1 nickel(II) oxalate 
• 7047-99-6 cerium(III) oxalate 
• 14100-65-3 metaborate 

Relevant articles and documents

Electrochemical Reduction of Carbon Dioxide Using Iron-Sulfur Clusters as Catalyst Precursors

The potential-current relationships of DMF solutions of a series of iron-sulfur compounds have revealed that in the presence of clusters 2- (R=PhCH2 or But) and 3- (M=Mo or W) the electroreduction of CO2 proceeds at the potential shifted by about 0.7 and 0.5 V, respectively, to the positive direction compared to the potential at which CO2 is reduced without any catalyst.When controlled potential electrolysis of a DMF solution containing 2- was carried out under CO2 at -2.0 V vs.SCE, phenylacetate and formate were formed as the products resulting from CO2 reduction.The cubane structure of this cluster collapsed rapidly under these conditions.However, when excess amount of PhCH2SH was added to the catholyte, the cluster structure was preserved during a relatively long period of electrolysis, and the yield of phenylacetate increased but that of formate decreased compared with the reaction in the absence of free PhCH2SH.

Polymerization-induced enhancement of binding and binding-induced polymerization

We obtained the binding free energy of the complex [Co(C2O 4)3]3- to the peptide H-Lys-Gly-(Lys-Gly) 9-Lys-NH2, and to the monomers (aminoacids) forming the peptide, using the electron transfer reaction between [Ru(NH3) 5pz]2+ and [Co(C2O4) 3]3- as the probe. The polymerization of the monomers increases the negative free energy of binding and changes its character, non-cooperative for the monomers and anti-cooperative for the peptide. This increase in the negative free energy represents a driving force for the polymerization process that produces the peptide from the aminoacids (monomers) in such a way that the polymerization in the presence of the cobalt complex is more favourable, from a thermodynamic point of view, in 16.5 kJ/mol.

Ultrasonic Irradiation of p-Nitrophenol in Aqueous Solution

The kinetics and mechanism of the sonochemical reactions of p-nitrophenol have been investigated in oxygenated aqueous solutions.In the presence of ultrasound (20 kHz, 84 W) p-nitrophenol was degraded primarily by denitration to yield NO2-, NO3-, benzoquinone, hydroquinone, 4-nitrocatechol, formate, and oxalate.These reaction products and the kinetic observations are consistent with a model involving high-temperature reactions of p-nitrophenol in the interfacial region of cavitation bubbles.The main reaction pathway appears to be carbon-nitrogen bond cleavage.Reaction with hydroxyl radicals provides a secondary reaction channel.The average effective temperature of the interfacial region surrounding the cavitation bubbles was estimated to be T ca. 800 K.