33809-77-7 Usage
Description
2-(ACETYLAMINO)BENZENECARBOXAMIDE, also known as benzamide substituted by an acetylamino group at position 2, is a member of the benzamides class. It is an antibiotic that has been isolated from Streptomyces aurantiogriseus and has demonstrated antifungal properties.
Uses
Used in Pharmaceutical Industry:
2-(ACETYLAMINO)BENZENECARBOXAMIDE is used as an antibiotic for its ability to inhibit the growth of certain bacteria, making it a valuable compound in the development of new medications to combat bacterial infections.
Used in Antifungal Applications:
In the field of antifungal treatment, 2-(ACETYLAMINO)BENZENECARBOXAMIDE is utilized as an antifungal agent to treat various fungal infections. Its effectiveness in inhibiting fungal growth can contribute to the development of new antifungal drugs and therapies.
Used in Research and Development:
2-(ACETYLAMINO)BENZENECARBOXAMIDE is also used as a research compound in the field of biochemistry and microbiology. Its properties and interactions with other molecules can provide valuable insights into the development of new drugs and therapies for both bacterial and fungal infections.
Synthesis Reference(s)
Tetrahedron Letters, 12, p. 1917, 1971 DOI: 10.1016/S0040-4039(01)96742-5
Check Digit Verification of cas no
The CAS Registry Mumber 33809-77-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,3,8,0 and 9 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 33809-77:
(7*3)+(6*3)+(5*8)+(4*0)+(3*9)+(2*7)+(1*7)=127
127 % 10 = 7
So 33809-77-7 is a valid CAS Registry Number.
InChI:InChI=1/C9H10N2O2/c1-6(12)11-8-5-3-2-4-7(8)9(10)13/h2-5H,1H3,(H2,10,13)(H,11,12)
33809-77-7Relevant articles and documents
Nitrile Hydration Reaction Using Copper Iodide/Cesium Carbonate/DBU in Nitromethane-Water
Kuwabara, Jun,Sawada, Yoshiharu,Yoshimatsu, Mitsuhiro
supporting information, p. 2061 - 2065 (2018/09/14)
The catalytic nitrile hydration (amide formation) in a copper iodide/cesium carbonate/1,8-diazabicyclo[5.4.0]undec-7-ene/nitromethane-water system is described. The protocol is robust and reliable; it can be applied to a broad range of substrates with high chemoselectivity.
Convenient N-acetylation of amines in N,N-dimethylacetamide with N,N-carbonyldiimidazole
Chikkulapalli, Anil,Aavula, Sanjeev Kumar,Mona Np, Rifahath,Karthikeyan, Karthikeyan,Kumar C.H., Vinodh,Sulur G., Manjunatha,Sumathi, Shanmugam
supporting information, p. 3799 - 3803 (2015/06/08)
Dimethylacetamide (DMAc) acts as an efficient source of acetyl and dimethylamine gas in the presence of N,N-carbonyldiimidazole (CDI). Addition of amines to the reaction mixture delivers the corresponding amides in good to excellent yields. The acetylation of amines reported herein, which relies on the in situ generation of N-acetylimidazole on warming of DMAc with CDI at 120-125 °C, serves as a convenient alternative to other acetylation methods.
COMPOSITIONS AND METHODS FOR MODULATING GATED ION CHANNELS
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Page/Page column 64-65, (2009/02/11)
Disclosed are compounds that modulate the activity of the gated ion channels. Compounds that modulate these gated ion channels are useful in the treatment of diseases and disorders related to pain, inflammation, the neurological system, the gastrointestinal system and genitourinary system. Preferred compounds include compounds of the Formulae 1, 2, 3, 4, and 5.
