3381-87-1 Usage
Description
2-Benzyloxybenzyl alcohol, with the molecular formula C14H14O2, is a white solid chemical compound characterized by a slightly sweet odor. It serves as a versatile building block in the synthesis of a variety of organic compounds, particularly in the production of pharmaceuticals, agrochemicals, and specialty chemicals. 2-BENZYLOXYBENZYL ALCOHOL is renowned for its utility as a protecting group for alcohols and phenols in organic synthesis, and also functions as a reagent in the preparation of numerous other compounds. Furthermore, 2-Benzyloxybenzyl alcohol has garnered interest due to its potential biological activities, such as antifungal and antibacterial properties.
Uses
Used in Pharmaceutical Industry:
2-Benzyloxybenzyl alcohol is utilized as a key intermediate in the synthesis of various pharmaceutical compounds. Its role as a protecting group for alcohols and phenols is crucial in organic synthesis, ensuring the selective protection of functional groups during multi-step reactions, which is vital for the development of new drugs.
Used in Agrochemical Industry:
In the agrochemical sector, 2-Benzyloxybenzyl alcohol is employed in the production of various agrochemicals. Its ability to act as a building block in the synthesis of complex organic molecules contributes to the creation of effective pesticides and other agricultural chemicals.
Used in Specialty Chemicals:
2-Benzyloxybenzyl alcohol is also used in the synthesis of specialty chemicals, where its versatility as a building block and protecting group is valuable for developing unique and specialized chemical products.
Used in Organic Synthesis Research:
As a reagent, 2-Benzyloxybenzyl alcohol is instrumental in the preparation of a multitude of other compounds, making it an essential component in organic synthesis research for both academic and industrial applications.
Used in Antimicrobial Applications:
2-Benzyloxybenzyl alcohol has been studied for its potential biological activities, including its antifungal and antibacterial properties. This makes it a candidate for use in applications requiring antimicrobial agents, such as in the development of new antibiotics or antifungal treatments.
Check Digit Verification of cas no
The CAS Registry Mumber 3381-87-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,3,8 and 1 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 3381-87:
(6*3)+(5*3)+(4*8)+(3*1)+(2*8)+(1*7)=91
91 % 10 = 1
So 3381-87-1 is a valid CAS Registry Number.
InChI:InChI=1/C14H14O2/c15-10-13-8-4-5-9-14(13)16-11-12-6-2-1-3-7-12/h1-9,15H,10-11H2
3381-87-1Relevant articles and documents
Nickel Hydride Catalyzed Cleavage of Allyl Ethers Induced by Isomerization
Kathe, Prasad M.,Berkefeld, Andreas,Fleischer, Ivana
supporting information, p. 1629 - 1632 (2021/02/09)
This report discloses the deallylation of O - and N -allyl functional groups by using a combination of a Ni-H precatalyst and excess Bronsted acid. Key steps are the isomerization of the O - or N -allyl group through Ni-catalyzed double-bond migration followed by Bronsted acid induced O/N-C bond hydrolysis. A variety of functional groups are tolerated in this protocol, highlighting its synthetic value.
Novel leucine ureido derivatives as aminopeptidase N inhibitors using click chemistry
Cao, Jiangying,Ma, Chunhua,Zang, Jie,Gao, Shuai,Gao, Qianwen,Kong, Xiujie,Yan, Yugang,Liang, Xuewu,Ding, Qin'ge,Zhao, Chunlong,Wang, Binghe,Xu, Wenfang,Zhang, Yingjie
, p. 3145 - 3157 (2018/06/01)
The over-expression of aminopeptidase N on diverse malignant cells is associated with the tumor angiogenesis and metastasis. In this report, one new series of leucine ureido derivatives containing the triazole moiety was designed, synthesized and evaluated as APN inhibitors. Among them, compound 13v showed the best APN inhibition with an IC50 value of 0.089 ± 0.007 μM, which was two orders of magnitude lower than that of bestatin (IC50 = 9.4 ± 0.5 μM). Compound 13v also showed dose-dependent anti-angiogenesis activities. Even at the lower concentration (10 μM), compound 13v presented similar anti-angiogenesis activity compared with bestatin at 100 μM in both the human umbilical vein endothelial cells (HUVECs) capillary tube formation assay and the rat thoracic aorta rings test. Moreover, compared with bestatin, 13v exhibited comparable, if not better in vivo anti-metastasis activity in a mouse H22 pulmonary metastasis model.
Highly Active Multidentate Ligand-Based Alkyne Metathesis Catalysts
Du, Ya,Yang, Haishen,Zhu, Chengpu,Ortiz, Michael,Okochi, Kenji D.,Shoemaker, Richard,Jin, Yinghua,Zhang, Wei
supporting information, p. 7959 - 7963 (2016/06/09)
Alkyne metathesis catalysts composed of molybdenum(VI) propylidyne and multidentate tris(2-hydroxylbenzyl)methane ligands have been developed, which exhibit excellent stability (remains active in solution for months at room temperature), high activity, an
