33871-62-4Relevant articles and documents
Intramolecular electron transfer and solvation
Simon, John D.,Su, Shyh-Gang
, p. 7016 - 7023 (1987)
The intramolecular charge transfer reaction and solvation dynamics of 4,4'- dimethylaminophenyl sulphone in alcohols are measured using picosecond time-resolved emission spectroscopy.The results are compared to theoretical models that treat the solvent as
Alkyl formates as reagents for reductive amination of carbonyl compounds
Afanasyev, Oleg I.,Cherkashchenko, Ilia,Kuznetsov, Anton,Kliuev, Fedor,Semenov, Sergey,Chusova, Olga,Denisov, Gleb,Chusov, Denis
, p. 112 - 113 (2020/03/03)
Alkyl formates in the presence of basic additives can serve as a reagent in the direct reductive amination of carbonyl compounds. The developed procedure can be applied to various aldehydes and ketones with electron donating and electron withdrawing groups.
On the dimensionality of the reaction coordinate of intramolecular charge-transfer reactions in protic solvents
Simon, John D.,Doolen, Robert
, p. 4861 - 4870 (2007/10/02)
Steady-state and time-resolved emission spectroscopies are used to examine the kinetics of intramolecular charge transfer in a series of bis[(N,N-dialkylamino)phenyl]sulfones in polar solvents. The experimental data are compared to theoretical models to d
Studies on 2,3,N,N'-substituted 4,4'-diaminodiphenylsulfones as potential antimalarial agents
Saxena,Saxena,Raina,Chandra,Sen,Anand,Seydel,Wiese
, p. 1081 - 1084 (2007/10/02)
A series of new 4,4'-diaminodiphenylsulfones substituted at 2 and 3 position and also at primary amino group of the phenyl rings have been synthesised and evaluated for their antimalarial activity against Plasmodium berghei infection in mice. Some of these compounds were active and showed complete inhibition of parasitaemia which included 7a1-7a4, 7b3, 7b4 and 16a at 1 mg/kg i.p. for 4 days and 16a, at 0.3 mg/kg for 4 days. Some compounds tested for their synthetase inhibitory action in cell-free system isolated from P. berghei (7b1, 7b2 and 8b2) were found to be more active than diaminodiphenylsulphone. The difference in order of activity between these in vivo and in vitro tests may be due to differences in their pharmacokinetic properties.