338797-21-0

Basic information

• Product Name: 4-((R)-3-Methyl-piperazin-1-yl)-6-nitro-quinoline
• Synonyms: 4-((R)-3-Methyl-piperazin-1-yl)-6-nitro-quinoline
• CAS NO: 338797-21-0
• Molecular Weight: 272.307
• Mol File: 338797-21-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-((R)-3-Methyl-piperazin-1-yl)-6-nitro-quinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 4-((R)-3-Methyl-piperazin-1-yl)-6-nitro-quinoline(338797-21-0)
• EPA Substance Registry System: 4-((R)-3-Methyl-piperazin-1-yl)-6-nitro-quinoline(338797-21-0)

Safety Data

• Hazardous Substances Data: 338797-21-0(Hazardous Substances Data)

Upstream product

• 13675-94-0 4-chloro-6-nitroquinoline 
• 75336-86-6 (2R)-methylpiperazine 

Relevant articles and documents

Novel (4-piperazin-1-ylquinolin-6-yl) arylsulfonamides with high affinity and selectivity for the 5-HT(6) receptor.

The discovery of (4-piperazin-1-ylquinolin-6-yl) arylsulfonamides and their binding affinities for a selection of 5-HT and dopamine subreceptors is described. Many compounds show high affinity (pK(i)>8) for the 5-HT(6) receptor and >100-fold selectivity against a range of other receptors. Structure-activity relationships of these compounds are discussed.