33891-00-8Relevant articles and documents
Cleavage of 1,3-dicarbonyls through oxidative amidation
Biallas, Phillip,H?ring, Andreas P.,Kirsch, Stefan F.
supporting information, p. 3184 - 3187 (2017/04/21)
A mild and convenient protocol for the oxidative cleavage of 1,3-diketone compounds is described. Under metal-free conditions, the method converts the 1,3-dicarbonyls into amides when treated with (nBu4N)N3 and iodine in the presence of an amine at room temperature. Using this method, a range of 1,3-dicarbonyls with various structural motifs including sterically demanding substituents and ordinary functional groups were easily fragmented, and it is demonstrated that cyclic 1,3-dicarbonyls can be directly transformed into acyclic diamides through ring-opening. Initial mechanistic studies show that diazidation of the enol form is followed by nucleophilic substitution with the amine.
Tandem synthesis of N-alkylated amides from aldoximes and alcohols by using a Ru/Ir dual-catalyst system
Li, Feng,Qu, Panpan,Ma, Juan,Zou, Xiaoyuan,Sun, Chunlou
, p. 2178 - 2182 (2013/08/23)
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Synthesis of water-soluble diaza-1,2,5-thiadiazolo-cyclophanes
Hatta, Taizo,Kawano, Muneo,Imaizumi, Yuji,Tsuge, Akihiko,Moriguchi, Tetsuji,Maeda, Hironori,Tsuge, Otohiko
, p. 651 - 658 (2007/10/03)
The reaction of 3,4-bis(p-bromomethylphenyl)-1,2,5-thiadiazole (1) with bis(N-alkylaminomethyl)benzenes under high dilution conditions gave the diaza1,2,5-thiadiazolo[3.3.2]cyclophanes, while 1 reacted with xylylenediamines to give cupped diazathiadiazolo
