338985-68-5

Basic information

• Product Name: pyochelin
• Synonyms: pyochelin
• CAS NO: 338985-68-5
• Molecular Weight: 324.425
• Mol File: 338985-68-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: pyochelin(CAS DataBase Reference)
• NIST Chemistry Reference: pyochelin(338985-68-5)
• EPA Substance Registry System: pyochelin(338985-68-5)

Safety Data

• Hazardous Substances Data: 338985-68-5(Hazardous Substances Data)

Upstream product

• 262419-96-5 (4R)-2-(2-hydroxyphenyl)-4,5-dihydrothiazole-4-carboxylic acid N-methoxy-N-methylamide 
• 611-20-1 salicylonitrile 
• 115921-07-8 (R)-2-(2'-hydroxyphenyl)-4-methoxycarbonyl-4,5-dihydrothiazole 
• 115921-06-7 (R)-2-(2-hydroxyphenyl)-4,5-dihydro-1,3-thiazole-4-carboxylic acid 
• 14344-46-8 (R)-N-methylcysteine hydrochloride 
• 163526-41-8 2'-(2-hydroxyphenyl)-2'-thiazoline-4'-carboxaldehyde 

Relevant articles and documents

An improved stereocontrolled synthesis of pyochelin, siderophore of Pseudomonas aeruginosa and Burkholderia cepacia

A considerably improved stereocontrolled synthesis of pyochelin, a hydroxyphenylthiazolinylthiazolidine type of siderophore common to most strains of Pseudomonas aeruginosa and Burkholderia cepacia is described. 2'- (2-Hydroxyphenyl)-2'-thiazoline-4'-carboxaldehyde, a key molecule involved in this synthesis has been prepared by reduction of 2'-(2-hydroxyphenyl)-2'- thiazoline-4'-(N-methoxy,N-methyl) carboxamide with lithium aluminium hydride. The aldehyde was further coupled with (R)-N-methylcysteine to yield pyochelin. Under the conditions reported, epimerization at the C-4' center was considerably diminished.