339235-70-0

Basic information

• Product Name: 1-(3-nitrophenylsulfonyl)-4-phenylpiperazine
• Synonyms: 1-(3-nitrophenylsulfonyl)-4-phenylpiperazine
• CAS NO: 339235-70-0
• Molecular Weight: 347.395
• Mol File: 339235-70-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-(3-nitrophenylsulfonyl)-4-phenylpiperazine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3-nitrophenylsulfonyl)-4-phenylpiperazine(339235-70-0)
• EPA Substance Registry System: 1-(3-nitrophenylsulfonyl)-4-phenylpiperazine(339235-70-0)

Safety Data

• Hazardous Substances Data: 339235-70-0(Hazardous Substances Data)

Upstream product

• 92-54-6 4-phenyl-1-piperazine 
• 121-51-7 3-nitrobenzenesulphonyl chloride 

Downstream Products

• 1019851-36-5 1-(3-aminophenylsulfonyl)-4-phenylpiperazine 
• 1272003-79-8 C₂₄H₂₃N₅O₃S 

Relevant articles and documents

Design, synthesis and biological evaluation of new thalidomide analogues as TNF-α and IL-6 production inhibitors

Several thalidomide analogues were synthesized and compared to thalidomide and its more active analogue, lenalidomide, for their ability to inhibit the production of the pro-inflammatory cytokine tumour necrosis factor (TNF)-α and interleukin (IL)-6 by LPS-activated peripheral blood mononuclear cells (PBMCs). Among these compounds, two analogues containing sulfonyl group displayed interesting downregulation of TNF-α and IL-6 production.