339306-06-8

Basic information

• Product Name: Morpholine, 4-[(4-ethoxyphenyl)thioxomethyl]-
• CAS NO: 339306-06-8
• Molecular Formula: C13H17NO2S
• Molecular Weight: 251.349
• Mol File: 339306-06-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Morpholine, 4-[(4-ethoxyphenyl)thioxomethyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Morpholine, 4-[(4-ethoxyphenyl)thioxomethyl]-(339306-06-8)
• EPA Substance Registry System: Morpholine, 4-[(4-ethoxyphenyl)thioxomethyl]-(339306-06-8)

Safety Data

• Hazardous Substances Data: 339306-06-8(Hazardous Substances Data)

Upstream product

• 110-91-8 morpholine 
• 24313-64-2 N-benzylidene-4-ethoxyaniline 
• 25117-74-2 4-ethoxybenzonitrile 
• 10031-82-0 4-ethoxybenzaldehyde 

Downstream Products

• 619-86-3 4-(ethoxy)benzoic acid 

Relevant articles and documents

The Willgerodt-Kindler reaction in water: High chemoselectivity of benzaldehydes over acetophenones

Water has been found for the first time as a useful solvent in the Willgerodt-Kindler (WK) reaction for the synthesis of benzothiomorpholides in high yield at 80°C for 3 h. This novel approach confronts the WK protocol with a new situation in which water

Microwave-assisted rapid hydrolysis and preparation of thioamides by Willgerodt-Kindler reaction

Aldehydes and aryl alkyl ketones were efficiently transformed to thioamides with the same number of carbon atoms via Willgerodt-Kindler reaction under microwave irradiation in solvent-free conditions. The thioamides obtained were hydrolyzed to corresponding carboxylic acids with microwave dielectric heating in one minute. Both reactions are very fast and the yields are excellent.