3394-09-0 Usage
Description
1-(2-aminophenyl)thiourea, also known as APTU, is a chemical compound with the molecular formula C7H9N3S. It is a white crystalline powder that is commonly used in various industries due to its unique properties and potential applications.
Uses
Used in Organic and Analytical Chemistry:
1-(2-aminophenyl)thiourea is used as a reagent for the determination of trace amounts of copper. Its ability to react with copper ions makes it a valuable tool in the field of analytical chemistry for detecting and quantifying copper levels in samples.
Used in the Production of Rubber:
APTU is used as a chemical additive in the rubber industry. Its inclusion in the production process can enhance the properties of rubber, such as its strength, flexibility, and durability.
Used in the Production of Dyes:
1-(2-aminophenyl)thiourea is used as a starting material or intermediate in the synthesis of various dyes. Its chemical structure allows for the creation of a wide range of colors and shades, making it a versatile component in the dye industry.
Used in the Pharmaceutical Industry:
APTU has been studied for its potential applications in cancer treatment and as an anti-inflammatory agent. Its ability to interact with biological systems and modulate certain pathways makes it a promising candidate for the development of new drugs and therapies.
However, it is important to note that APTU should be handled with care, as it is considered to be a toxic and irritant substance. Proper safety measures and precautions should be taken when working with this compound to minimize the risk of exposure and potential health hazards.
Check Digit Verification of cas no
The CAS Registry Mumber 3394-09-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,3,9 and 4 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 3394-09:
(6*3)+(5*3)+(4*9)+(3*4)+(2*0)+(1*9)=90
90 % 10 = 0
So 3394-09-0 is a valid CAS Registry Number.
3394-09-0Relevant articles and documents
o-Phenylenediamine as a Source of Fused Azole, Azine, and Diazepine Derivatives
Almostafa, A. M.,Assy, M. G.,Ismail, N. A.,Shehta, W.
, p. 1152 - 1157 (2021/09/08)
Abstract: A facile synthetic approach to diazepine and/or benzimidazole derivatives has been developed through the reaction of enamine [N1-(1-phenylethenyl)benzene-1,2-diamine] obtained from o-phenylenediamine and acetophenone. Its reaction with isophthaloyl chloride produced bis(1,5-benzodiazepinyl)benzene derivative via cyclization involving the nucleophilic enamino carbon atom, whereas the cyclocondensation with diethyl succinate occurred at the nucleophilic nitrogen atom to give bis-benzimidazole derivative. Depending on the conditions, the cyclization with carbon disulfide in DMSO afforded tricyclic 4-phenylimidazo[4,5,1-hi]indole-2(1H)-thione, while 4-phenyl-1,3-dihydro-2H-1,5-benzodiazepine-2-thione was formed in the presence of pyridine. Cyclocondensation of o-phenylenediamine with two equivalents of acetophenone in acid medium produced 3-phenyl-1-(1-phenylethenyl)-1,4-dihydroquinoxaline. N-(2-Aminophenyl)thiourea obtained from o-phenylenediamine and ammonium thiocyanate reacted with chloroacetyl chloride, diethyl malonate, carbon disulfide, and sodium nitrite in aqueous HCl to afford benzimidazole, thiadiazolobenzimidazole, and benzotriazole derivatives.
