3395-82-2Relevant articles and documents
Method for synthesizing 4-tert-butyl benzaldehyde
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Paragraph 0023-0026; 0030-0032; 0037-0039, (2020/02/19)
The invention discloses a method for synthesizing 4-tert-butyl benzaldehyde and belongs to the technical field of organic synthesis. The method comprises the steps of subjecting benzaldehyde and triorthoformate to a reaction to produce benzaldehyde acetal, then, subjecting the benzaldehyde acetal and isobutene to a sealed reaction in the presence of a catalyst, and carrying out acid quenching, thereby obtaining the 4-tert-butyl benzaldehyde. According to the method, the 4-tert-butyl benzaldehyde is obtained through adopting benzaldehyde protection, then, firstly, becoming an electron donatingorientating group, and then, prompting selective localization of the isobutene by employing an appropriate catalyst; and a ratio of a 2-tert-butyl benzaldehyde isomer to the product is smaller than 1:14, and after the reaction ends up, the process is applicable to industrialized large-scale production.
P- tert-Butyl Groups Improve the Utility of Aromatic Protecting Groups in Carbohydrate Synthesis
Asano, Sachi,Tanaka, Hide-Nori,Imamura, Akihiro,Ishida, Hideharu,Ando, Hiromune
, p. 4197 - 4200 (2019/06/18)
Aromatic protective groups are widely used in carbohydrate synthesis owing to their numerous merits. However, they unpredictably make certain compounds insoluble in organic solvents owing to their π-stacking abilities. It was found that introducing a tert
Electrochemical deallylation of α-allyl cyclic amines and synthesis of optically active quaternary cyclic amino acids
Kirira, Peter G.,Kuriyama, Masami,Onomura, Osamu
experimental part, p. 3970 - 3982 (2010/07/04)
Electrochemical oxidation of α-allylated and α-betizylated N-acylated cyclic amines by using a graphite anode easily affords the corresponding α-methoxylated products with up to 76% yield. Ease of oxidation was affected by the type of electrode, the size