339554-01-7

Basic information

• Product Name: N-p-tolyl-anthraniloyl chloride
• CAS NO: 339554-01-7
• Molecular Weight: 245.708
• Mol File: 339554-01-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-p-tolyl-anthraniloyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: N-p-tolyl-anthraniloyl chloride(339554-01-7)
• EPA Substance Registry System: N-p-tolyl-anthraniloyl chloride(339554-01-7)

Safety Data

• Hazardous Substances Data: 339554-01-7(Hazardous Substances Data)

Upstream product

• 16524-23-5 N-p-tolyl-anthranilic acid 
• 106-49-0 p-toluidine 
• 88-67-5 2-Iodobenzoic acid 

Downstream Products

• 1415651-15-8 C₂₂H₂₀N₂O₃ 
• 1415651-20-5 C₂₄H₂₃ClN₂O₃ 

Relevant articles and documents

Synthesis and investigation of anti-inflammatory activity of novel nitric oxide donating hybrid drugs

A small library of nitric oxide donating groups, 4-acetamidophenyl-2-[{2- (nitrooxy)ethyl}(phenyl) amino]benzoate (5a-e) possessing a variety of substituents (-H, -NO2, -CH3, -acetamidophenyl, -SO 2NH2) attached to the fourth position of phenyl ring were synthesized and evaluated for anti-inflammatory, analgesic and ulcerogenic potential. Structure-activity relationship data showed that the 2-phenylaminobenzoic acid skeleton is required for selective COX-2 inhibition. Among all compounds 4-acetamidophenyl-2-[{2-(nitrooxy)ethyl}(phenyl)amino] benzoate (5a) has shown potent anti-inflammatory activity while 4-acetamidophenyl-2-[{4-{(4-acetamidophenoxy)carbonyl} phenyl}{2-(nitrooxy) ethyl}amino]benzoate (5d) has shown potent analgesic activity compared to standard drug diclofenac.