3396-01-8Relevant articles and documents
IRAK DEGRADERS AND USES THEREOF
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Paragraph 00607-00608; 00604, (2021/06/22)
The present invention provides compounds, compositions thereof, and methods of using the same.
In silico molecular docking, synthesis of 4-(4-benzoylaminophenoxy) phenol derivatives as androgen receptor antagonists
Elancheran, Ramakrishnan,Kabilan, Senthamaraikannan,Kotoky, Jibon,Ramanathan, Muthiah,Bhattacharjee, Atanu
, p. 307 - 316 (2019/09/12)
Aim and Objective: To study the structural difference, optimization, molecular docking and development of new benzoyl amino phenoxy phenol derivatives as anti-prostate cancer agents. Materials and Methods: Strategies towards the identification of novel be
Design, synthesis and antitumor activity of novel cis-furoquinoline derivatives
Li, Jie,Pei, Shuchen,Zhu, Yingxi,Wu, Jianbo,Chen, Yin,Zhang, Weiyu,Wu, Yong
, p. 379 - 388 (2012/07/03)
A series of novel cis-furoquinoline derivatives was synthesized and tested for their antitumor activities in vitro against HepG2 cells, Lu-04 cells and Leu02 cells to evaluate structure-activity relationships. Assay-based antiproliferative activity study revealed that several compounds had significant effects on cytotoxicity, among which compounds 2f, 2l, 2q were found to be the most active compounds. Above all, compounds 2f, 2l, 2q would be potential anticancer agents which deserved further research.