34039-36-6Relevant articles and documents
RENIN INHIBITORS
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, (2009/01/23)
The present invention is directed to aspartic protease inhibitors. The present invention is also directed to pharmaceutical compositions comprising the disclosed aspartic protease inhibitors. The present invention is further directed to methods of antagonizing one or more aspartic proteases in a subject in need thereof, and methods for treating an aspartic protease mediated disorder in a subject using the disclosed aspartic protease inhibitors.
Process for the preparation of 2-nitrobenzaldehydes
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, (2008/06/13)
The new process for the preparation of 2-nitrobenzaldehydes of the general formula STR1 in which X1 and X2 either independently of one another represent hydrogen or halogen or one of the substituents represents nitro and the other substituent then represents hydrogen, by oxidation of 2-nitrotoluenes of the general formula STR2 in which X1 and X2 have the meaning indicated above is characterized in that the oxidation with oxygen or an oxygen-containing gas is carried out in the presence of at least one alkoxyalkylamine as a solvent and in the presence of strong bases.