340771-31-5

Basic information

• Product Name: 1-ETHYNYL-4-(METHYLSULPHONYL)-BENZENE
• Synonyms: 1-ETHYNYL-4-(METHYLSULPHONYL)-BENZENE;4-(Methylsulfonyl)phenylacetylene;Benzene, 1-ethynyl-4-(Methylsulfonyl)-;1-Ethynyl-4-Methanesulfonyl-benzene;1-Ethynyl-4-(Methylsulfonyl)benzene;1-Ethynyl-4-(methylsulfonyl)
• CAS NO: 340771-31-5
• Molecular Formula: C₉H₈O₂S
• Molecular Weight: 180.22362
• Mol File: 340771-31-5.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 327.749°C at 760 mmHg
• Flash Point: 187.645°C
• Appearance: /
• Density: 1.254g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.571
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1-ETHYNYL-4-(METHYLSULPHONYL)-BENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-ETHYNYL-4-(METHYLSULPHONYL)-BENZENE(340771-31-5)
• EPA Substance Registry System: 1-ETHYNYL-4-(METHYLSULPHONYL)-BENZENE(340771-31-5)

Safety Data

• Hazardous Substances Data: 340771-31-5(Hazardous Substances Data)

Usage

General Description

1-Ethynyl-4-(methylsulphonyl)-benzene is a chemical compound containing carbon, hydrogen, sulphur, and oxygen. The name indicates its structure, with an ethynyl functional group (a hydrocarbon subunit with a triple bond) attached to the first carbon of a benzene ring, and a methylsulfonyl (a sulfonyl group with a methyl group attached) on the fourth carbon. It predominantly exists in a solid state and is often used in organic chemistry. As with many chemical compounds, it needs to be handled with care due to potential health and environmental hazards. The precise properties and reactivity of this compound can be determined through specific chemical analyses. Studies of this compound contribute to our overall understanding of organic chemistry and help develop new compounds and reactions.

InChI:InChI=1/C9H8O2S/c1-3-8-4-6-9(7-5-8)12(2,10)11/h1,4-7H,2H3

Upstream product

• 113854-19-6 trimethyl((4-(methylsulfonyl)phenyl)ethynyl)silane 
• 56041-85-1 4-ethynylthioanisole 
• 3466-32-8 4-bromoohenyl methyl sulfone 
• 10297-73-1 4-(methanesulfonyl)acetophenone 

Downstream Products

• 742699-85-0 3-(4-methanesulfonylphenyl)-1-(4-methylsulfanylphenyl)prop-2-yn-1-ol 
• 923026-49-7 4-[4-(methylsulfonyl)phenyl]-1-[(3-phenylprop-2-yn-1-yl)oxy]but-3-yn-2-one 
• 742699-86-1 3-(4-methanesulfonylphenyl)-1-(4-methylsulfanylphenyl)prop-2-yn-1-one 
• 918904-70-8 {4-[3-cyclohexylmethoxy-5-(4-methanesulfonyl-phenylethynyl)-phenyl-sulfanyl]-2-methyl-phenoxy}-acetic acid ethyl ester 
• 918904-72-0 {4-[3-cyclopentylmethoxy-5-(4-methanesulfonyl-phenylethynyl)-phenyl-sulfanyl]-2-methyl-phenoxy}-acetic acid ethyl ester 
• 1040264-69-4 C₃₅H₄₇N₇O₉S₂ 
• 1227370-71-9 4-fluoro-2-(4-methanesulfonyl-phenylethynyl)-benzaldehyde 
• 1338457-70-7 5-[p-(aminosulfonyl)phenyl]-1-(2',3',4'-tri-O-acetyl-D-glucuronic acid methyl ester)-1H-1,2,3-triazole 
• 1338457-72-9 5-[p-(aminosulfonyl)phenyl]-1-(2',3',4'-tri-O-acetyl-β-D-arabinopyranosyl)-1H-1,2,3-triazole 
• 1338457-80-9 5-[p-(aminosulfonyl)phenyl]-1-(β-D-arabinopyranosyl)-1H-1,2,3-triazole 
• 1338457-74-1 5-[p-(aminosulfonyl)phenyl]-1-(hepta-O-acetyl-β-D-maltopyranosyl)-1H-1,2,3-triazole 
• 1338457-64-9 5-[p-(aminosulfonyl)phenyl]-1-(2',3',4',6'-tetra-O-acetyl-β-D-glucopyranosyl)-1H-1,2,3-triazole 
• 1338457-76-3 5-[p-(aminosulfonyl)phenyl]-1-(β-D-glucopyranosyl)-1H-1,2,3-triazole 
• 1338457-66-1 5-[p-(aminosulfonyl)phenyl]-1-(2',3',4',6'-tetra-O-acetyl-β-D-galactopyranosyl)-1H-1,2,3-triazole 

Relevant articles and documents

Pyridylidene Amide Ru Complex for Selective Oxidation in Organic Synthesis

The ruthenium(II) bis(PYA) complex 1 (PYA = p-pyridylidene amide) is a powerful catalyst for the oxidation of sulfides to sulfones, of alkenes to carbonyl compounds, and of terminal alkynes to carboxylic acids by using NaIO4 as the terminal oxidant. The catalytic system shows a broad functional group tolerance and rate differences between alkyne and sulfide oxidation that are sufficiently large to effectively achieve selective sulfide oxidation with exquisite selectivity.

Novel valdecoxib derivatives by ruthenium?II)-promoted 1, 3-dipolar cycloaddition of nitrile oxides with alkynes - Synthesis and COX-2 inhibition activity

Novel valdecoxib-based cyclooxygenase-2 inhibitors were synthesized in one step via 1, 3-dipolar cycloaddition of nitrile oxides with a series of eleven aryl alkynes, six of them described for the first time. Application of Ru?II)-catalysis leads preferab

Transition-metal-free regioselective synthesis of alkylboronates from arylacetylenes and vinyl arenes

A transition-metal-free synthesis of alkylboronates, utilizing arylacetylenes or vinyl arenes and bis(pinacolato)diboron through tandem borylation and protodeboronation, has been developed. This reaction is efficient, practical and environmentally benign, leading to anti-Markovnikov products with excellent regioselectivity, broad functional group tolerance and excellent yields in both small and gram scales.