3411-58-3Relevant articles and documents
Enz,W.,Cecchinato,M.
, p. 706 - 709 (1961)
Reversible thiazolidine exchange: A new reaction suitable for dynamic combinatorial chemistry
Saiz, Cecilia,Wipf, Peter,Manta, Eduardo,Mahler, Graciela
supporting information; experimental part, p. 3170 - 3173 (2009/12/05)
New dynamic combinatorial libraries (DCLs) were generated using the reversible aminothiol exchange reaction of thiazolidines and aromatic aldehydes. The reaction proceeded in aqueous buffered media at pH 4 and room temperature to generate thermodynamically controlled mixtures of heterocycles. The synthesis of an enantiomerically pure thiazolidinyloxazolidine is also reported. The oxazolidine moiety could be exchanged in CH2Cl2 in the presence of catalytic p-TsOH.
A new approach to reductive deprotection of thioethers with a low-valent titanium reagent
Shadakshari,Talukdar,Chattopadhyay
, p. 1007 - 1010 (2007/10/03)
Low-valent titanium mediated cleavage of carbon-sulphur bond is reported. This has resulted in an efficient and mild protocol for the deprotection of allyl/benzyl thioethers under reductive condition and with good yields. Deprotection can be performed regio- and chemo-selectively in the presence of acid, ester and N-benzyl/allyl functionalities and is general for aliphatic and aromatic precursors.