3412-48-4

Basic information

• Product Name: L-(+)-α-phenylglycine N-carboxy anhydride
• Synonyms: L-(+)-α-phenylglycine N-carboxy anhydride
• CAS NO: 3412-48-4
• Molecular Weight: 177.159
• Mol File: 3412-48-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: L-(+)-α-phenylglycine N-carboxy anhydride(CAS DataBase Reference)
• NIST Chemistry Reference: L-(+)-α-phenylglycine N-carboxy anhydride(3412-48-4)
• EPA Substance Registry System: L-(+)-α-phenylglycine N-carboxy anhydride(3412-48-4)

Safety Data

• Hazardous Substances Data: 3412-48-4(Hazardous Substances Data)

Upstream product

• 2935-35-5 (S)-2-phenylglycine 
• 503-38-8 trichloromethyl chloroformate 
• 5491-18-9 (S)-N-(benzyloxycarbonyl)phenylglycine 
• 2900-27-8 (2S)-2-[(tert-butoxycarbonyl)amino]-2-phenylethanoic acid 
• 75-44-5 phosgene 

Downstream Products

• 1298016-01-9 3-phenyl-3,4-dihydro-1H-benzo[e][1,4]diazepine-2,5-dione 

Relevant articles and documents

An achiral manganese salen catalyst encapsulated in a peptidic phosphonate homochiral solid for the enantioselective formation of diols by consecutive epoxidation and hydration reactions

An insoluble, porous, amorphous, homochiral material based on a polypeptide titanium-phosphonate scaffold with an encapsulated achiral Mn III-salen was prepared and characterized. Consecutive epoxidation and hydration of styrene and its derivatives by aqueous hypochlorite in THF showed the highly enantioselective (>99%) formation of styrene diol derivatives.

New routes to 1,4-benzodiazepin-2,5-diones

1,4-benzodiazepin-2,5-diones have been synthesized in good overall yields by two routes, the first one by cyclisation of dipeptides prepared from Boc anthranilic acid and α-amino acid methyl esters, the second one by reaction of N-carboxy α-amino acid anhydrides with Boc anthranilic acid.