3412-76-8

Basic information

• Product Name: N,N'-DIBENZYLETHYLENEDIAMINE DIHYDROCHLORIDE
• Synonyms: dbeddihydrochloride;f212;n,n’-dibenzyl-ethylenediamindihydrochloride;N,N'-DIBENZYLETHYLENEDIAMINE DIHYDROCHLORIDE;RARECHEM AQ A1 0039;TIMTEC-BB SBB001289;N,N'-dibenzylethylenediammonium dichloride;1,2-Bis(benzylamino)ethanedihydrochloride
• CAS NO: 3412-76-8
• Molecular Formula: C₁₆H₂₀N₂*2ClH
• Molecular Weight: 313.27
• EINECS: 222-300-2
• Mol File: 3412-76-8.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 373.8°Cat760mmHg
• Flash Point: 220.5°C
• Appearance: /
• Density: g/cm³
• CAS DataBase Reference: N,N'-DIBENZYLETHYLENEDIAMINE DIHYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N,N'-DIBENZYLETHYLENEDIAMINE DIHYDROCHLORIDE(3412-76-8)
• EPA Substance Registry System: N,N'-DIBENZYLETHYLENEDIAMINE DIHYDROCHLORIDE(3412-76-8)

Safety Data

• Hazardous Substances Data: 3412-76-8(Hazardous Substances Data)

Usage

Description

N,N'-Dibenzylethylenediamine dihydrochloride is a white crystalline powder that is soluble in water and alcohol. It is a chemical compound commonly used as a reducing agent in organic synthesis and as an additive in plating processes.

Uses

Used in Organic Synthesis:
N,N'-Dibenzylethylenediamine dihydrochloride is used as a reducing agent in organic synthesis for its ability to facilitate chemical reactions and improve the yield of desired products.
Used in Plating Processes:
In the plating industry, N,N'-Dibenzylethylenediamine dihydrochloride is used as an additive to enhance the quality and performance of plated coatings.
Used in Pharmaceutical Production:
N,N'-Dibenzylethylenediamine dihydrochloride is utilized in the production of pharmaceuticals, contributing to the synthesis of various medicinal compounds.
Used in Pesticide Production:
This chemical compound is also used in the production of pesticides, playing a role in the development of effective and safe agrochemicals.
Used in Rubber Chemicals:
N,N'-Dibenzylethylenediamine dihydrochloride is employed in the manufacturing of rubber chemicals, which are essential for the production of various rubber goods.
Used in Dye and Textile Chemical Production:
Additionally, N,N'-Dibenzylethylenediamine dihydrochloride is often used in the preparation of dyes and textile chemicals, contributing to the coloration and finishing processes in the textile industry.
Safety Precautions:
It is important to handle N,N'-Dibenzylethylenediamine dihydrochloride with care, as it can cause skin and eye irritation. Moreover, it may be harmful if ingested or inhaled, necessitating proper safety measures during its use and storage.

Upstream product

• 74677-20-6 Bis(dibenzyl-1,3 imidazolidinyl-2)-1,4 diphenyl-1,4 butadiene-(1Z,3E) 
• 71201-44-0 meso-7,7'-bis-(1,4-dibenzyl-6-phenyl-1,2,3,4-tetrahydro-1,4-diazepinyl) 
• 71201-44-0 racemic-7,7'-bis-(1,4-dibenzyl-6-phenyl-1,2,3,4-tetrahydro-1,4-diazepinyl) 
• 100-52-7 benzaldehyde 
• 107-15-3 ethylenediamine 
• 104-71-2 N,N'-bis(benzyliden)ethylendiamine 
• 140-28-3 N,N'-Dibenzylethylenediamine 
• 10507-26-3 N,N'-dibenzylethylenediamine diacetate 

Downstream Products

• 69239-61-8 N,N'-Dibenzyl-N,N'-dinitroso-1,2-diaminoethane 
• 140-28-3 N,N'-Dibenzylethylenediamine 
• 1332367-79-9 dimethyl 6,6′([ethane-1,2-diylbis{benzylazanediyl}]bis[methylene])dipicolinate 

Relevant articles and documents

Rapid Thermodynamically Stable Complex Formation of [nat/111In]In3+, [nat/90Y]Y3+, and [nat/177Lu]Lu3+ with H6dappa

A phosphinate-bearing picolinic acid-based chelating ligand (H6dappa) was synthesized and characterized to assess its potential as a bifunctional chelator (BFC) for inorganic radiopharmaceuticals. Nuclear magnetic resonance (NMR) spectroscopy was employed to investigate the chelator coordination chemistry with a variety of nonradioactive trivalent metal ions (In3+, Lu3+, Y3+, Sc3+, La3+, Bi3+). Density functional theory (DFT) calculations explored the coordination environments of aforementioned metal complexes. The thermodynamic stability of H6dappa with four metal ions (In3+, Lu3+, Y3+, Sc3+) was deeply investigated via potentiometric and spectrophotometric (UV-vis) titrations, employing a combination of acidic in-batch, joint potentiometric/spectrophotometric, and ligand-ligand competition titrations; high stability constants and pM values were calculated for all four metal complexes. Radiolabeling conditions for three clinically relevant radiometal ions were optimized ([111In]In3+, [177Lu]Lu3+, [90Y]Y3+), and the serum stability of [111In][In(dappa)]3- was studied. Through concentration-, time-, temperature-, and pH-dependent labeling experiments, it was determined that H6dappa radiolabels most effectively at near-physiological pH for all radiometal ions. Furthermore, very rapid radiolabeling at ambient temperature was observed, as maximal radiolabeling was achieved in less than 1 min. Molar activities of 29.8 GBq/μmol and 28.2 GBq/μmol were achieved for [111In]In3+ and [177Lu]Lu3+, respectively. For H6dappa, high thermodynamic stability did not correlate with kinetic inertness-lability was observed in serum stability studies, suggesting that its metal complexes might not be suitable as a BFC in radiopharmaceuticals.

Synthesis and supramolecular features of hybrid POM/onium solid-state assemblies

Polyoxomolybdate-based organic-inorganic hybrid architectures were synthesised and characterised by X-ray crystallography. The supramolecular assemblies present rows of metallic clusters H-bonded by ammonium cations, with a 1:2 molybdate/ammonium ratio. The organic moieties of the ammonium cations establish hydrophobic contact among them such as van der Waals, C-Hπ and ππ interactions that stabilise the supramolecular architectures. In particular, for compound 5 the n-alkyl tails pack closely together giving a lipid-like bilayer. In compound 6, the aromatic phenyl rings of the organic cation allow the stabilisation of the supramolecular architecture by C-Hπ and ππ interactions. Regarding the X-ray structure of the compound 11, the tetraanionic octa-molybdate [Mo8O26]4- cluster is surrounded by four ethyl-triphenyl-phosphonium cations. Running along the b-axis open channels are occupied by DMF solvent molecules. Interestingly, a soaking experiment in n-pentane with the corresponding crystals of compound 11 afforded to a crystal structure very different from the native one. Van der Waals, C-Hπ and ππ interactions between large organic moieties are fundamental in the stabilization of hybrid organic-inorganic POM architectures.

Synthesis of N,N'-Dibenzylethylenediamine via Palladium-Carbon-catalysed Reductive Alkylation

Reductive alkylation of ethylenediamine with benzaldehyde and hydrogen in the presence of Pd-C has been investigated in order to optimize the synthesis of N,N'-dibenzylethylenediamine; the efficiency of the procedure has been improved by minimizing undesired competing reactions of cyclization and hydrogenolysis.