34164-94-8

Basic information

• Product Name: 2-(4-Chlorophenyl)imidazo[1,2-a]pyridin-3-amine
• Synonyms: 2-(4-Chlorophenyl)imidazo[1,2-a]pyridin-3-amine
• CAS NO: 34164-94-8
• Molecular Formula: C₁₃H₁₀ClN₃
• Molecular Weight: 243.7
• Mol File: 34164-94-8.mol
• Article Data: 5

Chemical Properties

• Melting Point: 146-148 °C
• Appearance: /
• Density: 1.36±0.1 g/cm3(Predicted)
• PKA: 7.68±0.50(Predicted)
• CAS DataBase Reference: 2-(4-Chlorophenyl)imidazo[1,2-a]pyridin-3-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-Chlorophenyl)imidazo[1,2-a]pyridin-3-amine(34164-94-8)
• EPA Substance Registry System: 2-(4-Chlorophenyl)imidazo[1,2-a]pyridin-3-amine(34164-94-8)

Safety Data

• Hazardous Substances Data: 34164-94-8(Hazardous Substances Data)

Usage

Structure

Imidazo[1,2-a]pyridine derivative with a 4-chlorophenyl group attached to the imidazole ring

Pharmacological activities

Potential activities of interest in medicinal chemistry research

Applications

May have applications in the development of drugs targeting specific biological pathways or receptors

Value in research

Structure and properties make it a valuable tool for studying structure-activity relationships of related compounds and for designing new chemical entities with desired biological activities.

Further research needed

To fully understand the potential uses and properties of the compound.

Upstream product

• 859359-24-3 N-2-(2,4,4-trimethylpentan-2-yl) 2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-amine 
• 601468-08-0 N?(tert?butyl)?2?(4?chlorophenyl)imidazo[1,2?a]pyridin?3?amine 
• 1323381-60-7 N-(4-chlorobenzylidene)[2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl]amine 
• 504-29-0 2-aminopyridine 
• 119072-55-8 tert-butylisonitrile 
• 104-88-1 4-chlorobenzaldehyde 

Relevant articles and documents

Skeletal diverse synthesis of N-fused polycyclic heterocycles via the sequence of Ugi-type MCR and CuI-catalyzed coupling/tandem Pictet-Spengler reaction

Several diversity-oriented syntheses of N-fused polycyclic heterocycles have been demonstrated but most of them are based on point diversity within the same library and usually involve time-consuming sequential multistep syntheses, which also suffer from

(Bromodimethylsulfonium) bromide-catalyzed one-pot three-component synthesis of imidazo[1,2-a]pyridines

Figure represented. (Bromodimethylsulfonium) bromide-catalyzed one-pot multicomponent reaction of 2-aminopyridine with aromatic aldehyde(s) and TMSCN yielding N-benzylidene-2-phenylimidazo[1,2-a]pyridines exclusively has been described. The reaction is so

An efficient, regioselective, versatile synthesis of N-fused 2- and 3-aminoimidazoles via Ugi-type multicomponent reaction mediated by zirconium(IV) chloride in polyethylene glycol-400

An Ugi-type multicomponent reaction of heterocyclic amidines with aldehydes and isocyanides catalyzed by zirconium(IV) chloride in PEG-400 was developed. The protocol offers the rapid, environment friendly, regioselective and versatile synthesis of medici