342037-21-2Relevant articles and documents
The spectroelectrochemical behaviour of redox-active manganese salen complexes
Solomon, Marcello B.,Jolliffe, Katrina A.,D'Alessandro, Deanna M.,Chan, Bun,Kubiak, Clifford P.
supporting information, p. 3704 - 3713 (2019/04/25)
Salens are well-known for their ability to catalyse electrochemical transformations; however, despite their rich history, the fundamental reduction chemistry of these systems remains relatively unexplored. This work reports the design and synthesis of eight discrete, functionalised Mn(iii) pyridyl salen metal complexes, in which the diamine is varied. The electrochemical properties of the complexes were examined using cyclic voltammetry (CV), spectroelectrochemical (SEC) techniques and Density Functional Theory (DFT) computational modelling to explore the mechanisms that underly Mn salen reduction chemistry. We briefly examine the electrochemistry of these complexes in the presence of CO2. These complexes represent potential ligands for incorporation into both discrete and extended metallosupramolecular assemblies.
IRE-1A INHIBITORS
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Page/Page column 100; 101, (2009/01/24)
Compounds which directly inhibit IRE-lα activity in vitro, prodrugs, and pharmaceutically acceptable salts thereof. Such compounds and prodrugs are useful for treating diseases associated with the unfolded protein response and can be used as single agents or in combination therapies.
SMALL ORGANIC MOLECULE REGULATORS OF CELL PROLIFERATION
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Page/Page column 317, (2008/12/05)
The present invention makes available methods and reagents for modulating proliferation or differentiation in a cell or tissue comprising contacting the cell with a compound. In certain embodiments, the methods and reagents may be employed to correct or inhibit an aberrant or unwanted growth state, e.g., by antagonizing a normal patched pathway or agonizing smoothened orhedgehog activity.
