3423-23-2

Basic information

• Product Name: 8-Azabicyclo[3.2.1]octan-3-ol, 8-(1-methylethyl)-, exo-
• Synonyms: 8-isopropyl-nortropane-3exo-ol;(1R,3S,5S)-8-Isopropyl-8-aza-bicyclo[3.2.1]octan-3-ol;8-Isopropyl-nortropan-3exo-ol
• CAS NO: 3423-23-2
• Molecular Formula: C10H19NO
• Molecular Weight: 169.267
• Mol File: 3423-23-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 8-Azabicyclo[3.2.1]octan-3-ol, 8-(1-methylethyl)-, exo-(CAS DataBase Reference)
• NIST Chemistry Reference: 8-Azabicyclo[3.2.1]octan-3-ol, 8-(1-methylethyl)-, exo-(3423-23-2)
• EPA Substance Registry System: 8-Azabicyclo[3.2.1]octan-3-ol, 8-(1-methylethyl)-, exo-(3423-23-2)

Safety Data

• Hazardous Substances Data: 3423-23-2(Hazardous Substances Data)

Upstream product

• 3423-28-7 8-aza-8-isopropyl-bicyclo<3.2.1>octan-3-one 

Downstream Products

• 145449-97-4 2-Phenyl-cyclohex-2-enecarboxylic acid (1R,3S,5S)-8-isopropyl-8-aza-bicyclo[3.2.1]oct-3-yl ester 
• 145450-00-6 (1R,3S,5S,8R)-8-Isopropyl-8-methyl-3-(2-phenyl-cyclohex-2-enecarbonyloxy)-8-azonia-bicyclo[3.2.1]octane; iodide 

Relevant articles and documents

PHOSPHINERHODIUM COMPLEXES AS HOMOGENEOUS CATALYSTS. XVI. STEREOSELECTIVE HYDROGENATION OF CYCLIC KETONES

Cyclic ketones have been hydrogenated stereoselectively with various phosphinerhodium complexes as catalysts.Systems containing phosphines of high basicity and consequently forming RhIII dihydrides as active species yielded mainly the thermodynamically more stable alcohol isomers.Catalysts prepared from aryl-type phosphines of low basicity and modified with Et3N, which contain RhI monohydrides as active complexes, afforded the less stable alcohol isomers as the major products.The ratio of RhIII and RhI hydrides, which determines the stereoselectivity of the catalysts prepared in situ could be changed by suitable choice of base.