342422-23-5Relevant articles and documents
KIF18A INHIBITORS
-
Paragraph 0189; 0248-0249, (2021/02/12)
Compounds of formula (I): as defined herein, and synthetic intermediates thereof, which are capable of modulating KIF18A protein thereby influencing the process of cell cycle and cell proliferation to treat cancer and cancer-related diseases. The invention also includes pharmaceutical compositions, including the compounds, and methods of treating disease states related to the activity of KIF18A.