342435-24-9Relevant articles and documents
A class of FLT3 kinase inhibitors, preparation and application thereof
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Paragraph 0262; 0265-0267, (2020/06/20)
The invention relates to a class of FLT3 kinase inhibitors, preparation and application thereof, wherein specifically the compound has a structure represented by a formula (I), and all groups and substituents are defined in the specification. The invention also discloses a preparation method of the compound, and application of the compound in inhibition of FLT3.
Imidazopyridazine IRAK4 inhibitor, and preparation method and application thereof
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Paragraph 0276; 0277; 0278, (2018/03/26)
The invention belongs to the field of medicines, and especially relates to an imidazopyridazine compound or a pharmaceutically acceptable salt thereof, a preparation method thereof, and an applicationof a medicinal composition of the compound or the salt in the treatment of tumors, inflammations, immunity and other diseases. The imidazopyridazine compound is a novel protein kinase IRAK4 inhibitor, and can selectively inhibit IRAK4 and downstream signaling pathways thereof. The compound has the structural formula I.