34258-14-5

Basic information

• Product Name: H-GLY-D-PHE-OH
• Synonyms: GLYCYL-D-PHENYLALANINE;GLY-D-PHE;H-GLY-D-PHE-OH
• CAS NO: 34258-14-5
• Molecular Formula: C₁₁H₁₄N₂O₃
• Molecular Weight: 222.24
• Product Categories: Dipeptides;Dipeptides and Tripeptides;Peptides
• Mol File: 34258-14-5.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 492.2°Cat760mmHg
• Flash Point: 251.5°C
• Appearance: /
• Density: 1.259g/cm³
• Vapor Pressure: 1.67E-10mmHg at 25°C
• Refractive Index: 1.576
• Storage Temp.: −20°C
• CAS DataBase Reference: H-GLY-D-PHE-OH(CAS DataBase Reference)
• NIST Chemistry Reference: H-GLY-D-PHE-OH(34258-14-5)
• EPA Substance Registry System: H-GLY-D-PHE-OH(34258-14-5)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 34258-14-5(Hazardous Substances Data)

Usage

Uses

Glycyl-D-phenylalanine is a tetrapeptide compound, used in preparation method and application.

InChI:InChI=1/C11H14N2O3/c12-7-10(14)13-9(11(15)16)6-8-4-2-1-3-5-8/h1-5,9H,6-7,12H2,(H,13,14)(H,15,16)/t9-/m1/s1

Upstream product

• 6780-38-7 N-phthaloylglycine chloride 
• 673-06-3 D-(R)-phenylalanine 
• 137503-97-0 N-Chloroacetyl-D-phenylalanine 
• 54885-66-4 Z-Gly-D-Phe-OH 
• 21685-51-8 D-phenylalanine methyl ester 
• 73538-53-1 methyl cbz-glycyl-D-phenylalaninate 
• 721-66-4 glycylphenylalanine 

Downstream Products

• 23927-19-7 (R)-3-benzyl-2,5-piperazinedione 
• 79814-48-5 N-Ac-Gly-D-Phe 
• 1080025-92-8 (R)-2-(2-(2-(1H-indol-3-yl)acetamido)acetamido)-3-phenylpropanoic acid 
• 1080025-93-9 (R)-2-(2-(3-(1H-indol-3-yl)propanamido)acetamido)-3-phenylpropanoic acid 

Relevant articles and documents

Noncovalent chirality sensing ensembles for the detection and reaction monitoring of amino acids, peptides, proteins, and aromatic drugs

Ternary complexes between the macrocyclic host cucurbit[8]uril, dicationic dyes, and chiral aromatic analytes afford strong induced circular dichroism (ICD) signals in the near-UV and visible regions. This allows for chirality sensing and peptide-sequence recognition in water at low micromolar analyte concentrations. The reversible and noncovalent mode of binding ensures an immediate response to concentration changes, which allows the real-time monitoring of chemical reactions. The introduced supramolecular method is likely to find applications in bioanalytical chemistry, especially enzyme assays, for drug-related analytical applications, and for continuous monitoring of enantioselective reactions, particularly asymmetric catalysis. Strong and diagnostic induced circular dichroism signals in the near-UV or visible region are obtained when chiral, optically transparent analytes bind to an achiral chemosensing ensemble composed of a macrocyclic host and dye. This affords a novel, supramolecular detection method for chiral aromatic analytes in water.