342901-76-2Relevant articles and documents
Synthetic studies on ciguatoxin: A highly convergent synthesis of the GHIJKLM ring system based on b-alkyl suzuki coupling
Takakura, Hiroyuki,Noguchi, Katsuhiko,Sasaki, Makoto,Tachibana, Kazuo
, p. 1090 - 1093 (2001)
Access to polycyclic polyethers is facilitated by a synthetic strategy involving two-step B-alkyl Suzuki coupling reactions for the stereo-selective construction of the polyether skeleton. Thus, a convergent synthetic route to the heptacyclic GHIJKLM ring system 1 of ciguatoxin, a marine algal toxin implicated in ciguatera fish poisoning, was developed. Bn = benzyl.